A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs

@MKBHolt @GilesYeo I ❤ the Labrador vs Flabrador story, told by a wonderful storyteller! https://t.co/zmoFv1eKLM

@GilesPalaeoLab I am guessing you know about this... https://t.co/D5Gv0T2duQ. We call our labradoodle a poobrador as she has all the undesirable traits. 😂

@StephenORahilly @ESRogs Well now I'm embarrassed because that paper was also from @StephenORahilly group 😁 https://t.co/5kj7jghT2j

@ultimatellama @Kika_GuideDog Definitely! Lucy could eat her dinner in less than 20 s. Labs often have a mutation in a pathway that controls appetite and it's more common in assistance dogs maybe because food motivation makes them more trainable https://t.

RT @timfrayling: but this is comfortably the best dog genetics story :-) - a defect to the same gene that causes severe obesity in kids, ma…

My favourite is this one, where a direct to consumer testing company reported a dog 'would probably be great for quick movements like boxing and basketball, and that she has the cardiac output for long endurance bike rides' https://t.co/Xt3gTV5sz1

but this is comfortably the best dog genetics story :-) - a defect to the same gene that causes severe obesity in kids, makes for great guide dogs: https://t.co/7j5AMrO9EU

@Gc8Mercedes This is a cool paper!

@LauredelaVega Laure, have a look at this papers from colleagues few years ago....chocolate labs are always humgry. https://t.co/uuTt5ST7Sh

A genetic basis for why my lab eats everything! https://t.co/HxCbtnC0EX

These lads eat anything. https://t.co/FgmA0QfJnx

@so_sroy @Leschevaliers1 @nalamoore_ Probablement avec une mutation dans le gène POMC 😉 https://t.co/ALPyiItsi8

Eh bien, figurez-vous qu’environ 25% des labradors ont une mutation dans le gène POMC. https://t.co/ALPyiItsi8

@bealelab @FlossieTeacake Absolutely! Labradors are lovely too, but have appetite issues owing to a deletion in the POMC gene... https://t.co/ugaMsv51pq

i've spent wayy too much time (instead of studying) thinking about how some labradors are genetically prone to be obese and they can't stop eating when food is put in front of them https://t.co/ZC1BFlyKyB

@knsstxs @KlutheScience https://t.co/oaZrQtMJU1

https://t.co/cvtgWQdRNK whats good for the goose is good for the gander https://t.co/cvtgWQdRNK

@lepinkainen @qikipedia https://t.co/5HdI3bHJzj

@Eva_Romera Es por una mutación en MC4R y el gen agoutí. Provoca que haya poca eumelanina y antagonismo para la saciedad. https://t.co/t2Of6K3frN

@tednaiman Every feline is different. Every canine is different, too. https://t.co/asNmDTo7Up Every human.... I think you get the gist!

@MorganPfiffner @whsource May also be confounded by the fact that this breed in particular is vry prone to appetite & satiety issues genetically? I've had several breeds of dogs; some self-regulate very well (ie leave food in the bowl) others can eat t

@Don_lyall @GDB_official I also remember seeing Sir O'Rahilly present this in SD in 2014 https://t.co/gO2dJZb85V

RT @darrenlogan: Raffan: About 25% of Labradors have a inactivating mutation in POMC, a key appetite regulating hormone. https://t.co/b7m6W…

There you go, Labradors have more food motivation and are prone to obesity due to a gene mutation. The genetic... https://t.co/Q01VaENgPp

RT @darrenlogan: Raffan: About 25% of Labradors have a inactivating mutation in POMC, a key appetite regulating hormone. https://t.co/b7m6W…

RT @darrenlogan: Raffan: About 25% of Labradors have a inactivating mutation in POMC, a key appetite regulating hormone. https://t.co/b7m6W…

Raffan: About 25% of Labradors have a inactivating mutation in POMC, a key appetite regulating hormone. https://t.co/b7m6WRwV7G #ECRO2017

RT @kdinbburg: A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retrievers https://t.co/…

The Genetics of Pooched-Out Pooches: Obesity #gene candidate found in Labrador Dogs https://t.co/hCLbmC5bGp #OA: https://t.co/AHGPVRA8CS https://t.co/iTXngQw41b

Nice article by @rkhamsi on a 14 bp deletion in POMC that increases appetite in Labrador retrievers. https://t.co/VAMi4R7mOK https://t.co/2e0zMk0H7f

RT @sketchscience: Nice paper! @EllieRaffan @GOdogsProject @Cell_Metabolism https://t.co/nnZW5Dq8aS https://t.co/HRWDYRGKrZ

RT @sketchscience: Nice paper! @EllieRaffan @GOdogsProject @Cell_Metabolism https://t.co/nnZW5Dq8aS https://t.co/HRWDYRGKrZ

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @GOdogsProject: @GOdogsProject made the #altmetrictop100 @GilesYeo @odonovcj @TheFatVet https://t.co/x6aU3np4U5 via @altmetric https:…

RT @PaulBrowne55: Well done @GilesYeo and the rest of the @GOdogsProject team! #altmetrictop100 https://t.co/VUTZAdVwmg

RT @GOdogsProject: @GOdogsProject made the #altmetrictop100 @GilesYeo @odonovcj @TheFatVet https://t.co/x6aU3np4U5 via @altmetric https:…

RT @PaulBrowne55: Well done @GilesYeo and the rest of the @GOdogsProject team! #altmetrictop100 https://t.co/VUTZAdVwmg

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

The POMC route to PORK…. In labs. Ht @TheFatVet https://t.co/x0LX8UvAiV

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

@GOdogsProject made the #altmetrictop100 @GilesYeo @odonovcj @TheFatVet https://t.co/x6aU3np4U5 via @altmetric https://t.co/ee6Jg2xlsz

RT @MRC_Epid: Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t…

Well done @GilesYeo and the rest of the @GOdogsProject team! #altmetrictop100 https://t.co/VUTZAdVwmg

Congratulations to @GOdogsProject on making the 2016 #altmetrictop100 for paper on appetite and weight in Labradors https://t.co/gu2Yjvxm6s! https://t.co/27hJA7jjZB

@spwells @razibkhan Hopefully results in neat insights like the Labrador POMC study https://t.co/KWAhINdbcO

@CamVetSchool Looking forward to it! But if anyone is interested in why Labs are prone to obesity, read our paper https://t.co/9ELNMKBrE7

@garytaubes or maybe it's just over breeding? https://t.co/okQ5vhozFp

RT @timfrayling: @BioMickWatson The most fascinating dog genome study? Are guide dogs so trainable because they're hungry? : https://t.co/N…

RT @timfrayling: @BioMickWatson The most fascinating dog genome study? Are guide dogs so trainable because they're hungry? : https://t.co/N…

@BioMickWatson The most fascinating dog genome study? Are guide dogs so trainable because they're hungry? : https://t.co/NIlFfWtKMP #GS2016

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs https://t.co/u4gC2ru99Y

@GOdogsProject 3/3 And how might being a Lab with a POMC mutation alter your MRI response to a treat? https://t.co/BVDWoF2MvK

RT @F1000: We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co…

We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co/9YRQeglvQ4

RT @F1000: We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co…

RT @F1000: We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co…

RT @F1000: We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co…

We’re gonna need a bigger collar: genetics behind the tendency of Labradors to become obese https://t.co/YbzEtPaHxq https://t.co/rfTUur8yKY

RT @GOdogsProject: Our GOdogs article was recommended on F1000Prime (@F1000) https://t.co/74TbMXSaJk Thanks @LoraHeisler!

Our GOdogs article was recommended on F1000Prime (@F1000) https://t.co/74TbMXSaJk Thanks @LoraHeisler!

Obesity-prone labrador retrievers have a deletion in the POMC neuropeptide gene https://t.co/I40YkZdNNV

RT @sketchscience: Nice paper! @EllieRaffan @GOdogsProject @Cell_Metabolism https://t.co/nnZW5Dq8aS https://t.co/HRWDYRGKrZ

RT @tomclearwood: labradors get fat because of a mutation that also makes them easily trainable... https://t.co/vq1RAYASWY #dogs https://t.…

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs… https://t.co/jgduXHonFI

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs https://t.co/sp2D8837MB

RT @antlp33: A possible reason why Labrador Retrievers are more prone to obesity https://t.co/7AefsttH70

RT @antlp33: A possible reason why Labrador Retrievers are more prone to obesity https://t.co/7AefsttH70

A possible reason why Labrador Retrievers are more prone to obesity https://t.co/7AefsttH70

Pourquoi les labradors ont-ils toujours faim ? https://t.co/veZwOgNCVD (+ https://t.co/OHoPBDZ46M )

Mutation du gène de la pro-opiomélanocortine et obésité chez le labrador (Cell Metabolism). https://t.co/NjfrHesBZt https://t.co/79QnUXX7At

RT @DanGraur: A frameshift mutation in the POMC gene is associated with increased weight & appetite in Labrador retrievers. https://t.co/E…

RT @DanGraur: A frameshift mutation in the POMC gene is associated with increased weight & appetite in Labrador retrievers. https://t.co/E…

A frameshift mutation in the POMC gene is associated with increased weight & appetite in Labrador retrievers. https://t.co/EWTFc02QB5

dikke labradors missen vaak een stuk van hun POMC-gen https://t.co/usEV3lUYFr

RT @sketchscience: Nice paper! @EllieRaffan @GOdogsProject @Cell_Metabolism https://t.co/nnZW5Dq8aS https://t.co/HRWDYRGKrZ

Nice paper! @EllieRaffan @GOdogsProject @Cell_Metabolism https://t.co/nnZW5Dq8aS https://t.co/HRWDYRGKrZ

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs https://t.co/wFxCyUuJzm

Is dog obesity in the genes? Breaking new research on causes of dog obesity have come out: https://t.co/hgnXHLlC5b

Why some labradors are prone to Obesity https://t.co/QFuGEmUNwe.

ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP　https://t.co/sFUO77owiz　複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https://t.co/rTmm0WwwQs

#labrador #labradorretriever #DNA Genet til Labrador,mangler av-knappen,til metthet/sult https://t.co/ZjUaZIXSg5 https://t.co/qD4OLiMcYZ

ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP　https://t.co/sFUO77owiz　複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https://t.co/rTmm0WwwQs

RT @OrenoSource: ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP https://t.co/iKXMas3aLL 複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https:…

RT @OrenoSource: ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP https://t.co/iKXMas3aLL 複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https:…

ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP　https://t.co/sFUO77owiz　複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https://t.co/rTmm0WwwQs

Labrador owners: why your dog likes to eat, is written in its genes (POMC gene deletion) https://t.co/kONT9tl4xB

Obesity-Prone Labrador Retrievers have a deletion in POMC gene @Cell_Metabolism #obesity #dogs #labrador https://t.co/Ng1HiXqEfV

RT @tschwarzromond: @GilesYeo, S. O'Rahilly report on POMC-deletion in obesity-prone #Labradors @molecularmetabolism @Cell_Metabolism http…

Wonder why your Lab begs for food? Battles the bulge? Looks like it is in the genes!... https://t.co/LcAdPN9iGO

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs. https://t.co/qHvTLp7XNC

ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP　https://t.co/sFUO77owiz　複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https://t.co/rTmm0WwwQs

RT @OrenoSource: ラブラドルなど一部犬種、遺伝子変異で太りやすく AFP https://t.co/iKXMas3aLL 複数のホルモンの前駆体のPOMC遺伝子に欠失があると太りやすいほか、餌による動機づけを受けやすい（Cell Metab原著）→ https:…

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs https://t.co/YyShU83saD