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Good Research Practice in Non-Clinical Pharmacology and Biomedicine

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Attention for Chapter 285: Minimum Information in In Vivo Research.
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Chapter title
Minimum Information in In Vivo Research.
Chapter number 285
Book title
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Published in
Handbook of experimental pharmacology, September 2019
DOI 10.1007/164_2019_285
Pubmed ID
Book ISBNs
978-3-03-033655-4, 978-3-03-033656-1
Authors

Patrizia Voehringer, Janet R. Nicholson

Abstract

Data quality, reproducibility and reliability are a matter of concern in many scientific fields including biomedical research. Robust, reproducible data and scientific rigour form the foundation on which future studies are built and determine the pace of knowledge gain and the time needed to develop new and innovative drugs that provide benefit to patients. Critical to the attainment of this is the precise and transparent reporting of data. In the current chapter, we will describe literature highlighting factors that constitute the minimum information that is needed to be included in the reporting of in vivo research. The main part of the chapter will focus on the minimum information that is essential for reporting in a scientific publication. In addition, we will present a table distinguishing information necessary to be recorded in a laboratory notebook or another form of internal protocols versus information that should be reported in a paper. We will use examples from the behavioural literature, in vivo studies where the use of anaesthetics and analgesics are used and finally ex vivo studies including histological evaluations and biochemical assays.

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Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2019.
All research outputs
#11,552,115
of 14,579,856 outputs
Outputs from Handbook of experimental pharmacology
#315
of 443 outputs
Outputs of similar age
#193,124
of 266,113 outputs
Outputs of similar age from Handbook of experimental pharmacology
#3
of 4 outputs
Altmetric has tracked 14,579,856 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 443 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,113 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.