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HSF1 and Molecular Chaperones in Biology and Cancer

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Cover of 'HSF1 and Molecular Chaperones in Biology and Cancer'

Table of Contents

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    Book Overview
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    Chapter 1 Structural and Biochemical Properties of Hsp40/Hsp70 Chaperone System
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    Chapter 2 The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation
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    Chapter 3 Regulation of Hsf1 and the Heat Shock Response
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    Chapter 4 Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease
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    Chapter 5 The Multifaceted Role of HSF1 in Tumorigenesis
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    Chapter 6 Chaperome Networks – Redundancy and Implications for Cancer Treatment
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    Chapter 7 The Role of HSF1 and the Chaperone Network in the Tumor Microenvironment
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    Chapter 8 The Impact of the ER Unfolded Protein Response on Cancer Initiation and Progression: Therapeutic Implications
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    Chapter 9 The Right Tool for the Job: An Overview of Hsp90 Inhibitors
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    Chapter 10 Lessons Learned from Proteasome Inhibitors, the Paradigm for Targeting Protein Homeostasis in Cancer
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    Chapter 11 Reflections and Outlook on Targeting HSP90, HSP70 and HSF1 in Cancer: A Personal Perspective
Attention for Chapter 6: Chaperome Networks – Redundancy and Implications for Cancer Treatment
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