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In Vivo Cellular Imaging Using Fluorescent Proteins

Overview of attention for book
Cover of 'In Vivo Cellular Imaging Using Fluorescent Proteins'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Assessing Cancer Cell Migration and Metastatic Growth In Vivo in the Chick Embryo Using Fluorescence Intravital Imaging
  3. Altmetric Badge
    Chapter 2 The use of fluorescent proteins for intravital imaging of cancer cell invasion.
  4. Altmetric Badge
    Chapter 3 High-resolution in vivo imaging of fluorescent proteins using window chamber models.
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    Chapter 4 In vivo imaging of pancreatic cancer with fluorescent proteins in mouse models.
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    Chapter 5 Lentivirus-Based DsRed-2-Transfected Pancreatic Cancer Cells for Deep In Vivo Imaging of Metastatic Disease
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    Chapter 6 Noninvasive and Real-Time Fluorescence Imaging of Peritoneal Metastasis in Nude Mice
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    Chapter 7 Three-Dimensional In Vivo Imaging of Tumors Expressing Red Fluorescent Proteins
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    Chapter 8 Real-Time Visualization and Characterization of Tumor Angiogenesis and Vascular Response to Anticancer Therapies
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    Chapter 9 In Vivo Imaging of Human Cancer with Telomerase-Specific Replication-Selective Adenovirus
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    Chapter 10 Real-Time Fluorescence Imaging of Abdominal, Pleural, and Lymphatic Metastases
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    Chapter 11 Real-Time Imaging of Tumors Using Replication-Competent Light-Emitting Microorganisms
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    Chapter 12 GFP-Transgenic Animals for In Vivo Imaging: Rats, Rabbits, and Pigs
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    Chapter 13 The use of fluorescent proteins for developing cancer-specific target imaging probes.
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    Chapter 14 In Vivo Imaging of the Developing Mouse Embryonic Vasculature
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    Chapter 15 In Vivo Cellular Imaging Using Fluorescent Proteins
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    Chapter 16 What Does It Take to Improve Existing Fluorescent Proteins for In Vivo Imaging Applications?
  18. Altmetric Badge
    Chapter 17 In vivo imaging of oligonucleotide delivery.
  19. Altmetric Badge
    Chapter 18 Subcellular Imaging In Vivo: The Next GFP Revolution
Attention for Chapter 17: In vivo imaging of oligonucleotide delivery.
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Chapter title
In vivo imaging of oligonucleotide delivery.
Chapter number 17
Book title
In Vivo Cellular Imaging Using Fluorescent Proteins
Published in
Methods in molecular biology, June 2012
DOI 10.1007/978-1-61779-797-2_17
Pubmed ID
22700416
Book ISBNs
978-1-61779-796-5, 978-1-61779-797-2
Authors

Takeshita F, Takahashi RU, Onodera J, Ochiya T, Fumitaka Takeshita, Ryou-u Takahashi, Jun Onodera, Takahiro Ochiya

Abstract

RNA interference (RNAi) has rapidly become a powerful tool for drug-target discovery and therapeutics. Cancer is an important application for RNAi therapeutics, since abnormal gene regulation is thought to contribute to the pathogenesis and maintenance of the metastatic phenotype of cancer. Many oncogenic genes present enticing therapeutic target possibilities for RNAi. Small interfering RNA (siRNA) and microRNA (miRNA) are potent and specific examples of RNAi are able to silence tumor-related genes and multiple oncogenic pathways and appear to be a rational approach to inhibit tumor growth. In subsequent in vivo studies, an appropriate animal model must be developed for a better evaluation of gene-silencing effects on tumors. How to evaluate the effect of siRNA and miRNA in an in vivo therapeutic model is also important. Bioluminescence imaging is an optical imaging method that can evaluate RNAi in vivo.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 44%
Student > Master 2 22%
Lecturer 1 11%
Student > Ph. D. Student 1 11%
Unknown 1 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 22%
Medicine and Dentistry 2 22%
Agricultural and Biological Sciences 2 22%
Pharmacology, Toxicology and Pharmaceutical Science 1 11%
Chemical Engineering 1 11%
Other 0 0%
Unknown 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2012.
All research outputs
#18,308,895
of 22,668,244 outputs
Outputs from Methods in molecular biology
#7,828
of 13,037 outputs
Outputs of similar age
#113,753
of 147,842 outputs
Outputs of similar age from Methods in molecular biology
#30
of 45 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,037 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 147,842 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.

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