@_nickdavies Might be less dangerous: https://t.co/ywoSFdEM5L
Ook hier weer geen bijzonder gedrag van Sars-Cov-2. Houdt zich braaf aan wat andere (corona)virussen ook doen.
RT @kaggieguy: The "new" British variant B.1.1.7 has a mutated ORF8 gene. These mutations have been seen previously, and were less virulen…
@markvanasten Zie net dit in mijn tijdlijn, lijkt weer storm in glas water met die nieuwe variant.
Read this
So? We need harder Lockdown ??
Sounds like good news!
Interesting:
So just let it spread as more transmissible but way less deadly, live with it like we do thousands of other virus and let's get on with our lives... Basic risk assessment 101
La varianteeeeee ingleseeeeeee...in pratica, il raffreddore.
So Government & Media made the public feel this mutation was deadlier. More fearmongering as usual.
Så det KAN sluta med att man försöker bromsa en mutation som KAN vara mer smittsam men mindre dödlig. Intressant följa utvecklingen.
Covid 19 Singapore tested 131 people with deletion coronavirus from Jan 2020 to March 2020. One person came from wuhan then went to twiane:https://t.co/blcU8rwmqC: https://t.co/tdEEI57z1v
Covid 19: Deletion Gene dated Augest 29, 2020 lab reports :https://t.co/blcU8rwmqC:
@dronico @docjosiahboone @rjf_berger @Silviawhat #Mutation Schwächung von #ORF8 geht wahrscheinlich mit einem milderen Verlauf einher. Die Anzahl der Fälle steigt jedoch wahrscheinlich an. Netto-Effekt? Schwierig zu beurteilen... https://t.co/s9YrgI31fa
@The__Taybor It’s in phase with an ORF8 deletion. https://t.co/PjhYadcgpo
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
@KlaasNelissen @DasUlrike @drWouterArrazol Ja had preprint net gelinkt in draadje hierboven - interessante studie... Grootste vraag blijft age-specific infection fatality rate. Introductie stopcodon in ORF8 zou voor lagere virulentie kunnen zorgen zoals in
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
(5/8) Eerder geobserveerde minder pathogene SARS-CoV2 varianten, zoals een strain gesequeneerd in Singapore met een deletie in het ORF8 gen, https://t.co/TCRDpIioZp, zijn nadien uitgestorven en werden dus niet geselecteerd.
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
@trvrb I am sure you know this, but this is part of what's known about ORF8 and how its functional deletion may be an adaptive evolutive trait possibly linked to less severe viral pathogenicity (on its own): https://t.co/UG0p9vLD9h https://t.co/tIXmltAZB2
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
@R0bMoon But on the more positive side, maybe there is compensation from other mutations: https://t.co/s4YOcaM8ZI
@alfonzoPgr @RosebudRowie @UKCovid19Stats And a study from the Lancet too https://t.co/ZBfkGjnI1k
@JamesSteggles @SpingoC @theosanderson This is the study used to make that claim (afaik). Some patients in this one had ORF8 deletion, which is not the same but equivalent to the Q27Stop mutation in the B.1.1.7 variant. Note - variant in this study had non
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
RT @Kevin_McKernan: Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y…
Also note ORF8 deletions that are in phase with N501Y. These are reported to be an attenuated strain. So if the N501Y mutation screws up plasma treatment but are milder due to ORF8.. do we really care if it spreads faster? https://t.co/PjhYadcgpo
RT @genperisi: #Covid19 dun paylastigim virus ORF8 bolgesi delesyonu (parca eksilmesi) ve olasi daha hafif seyir hipotezi ORF8 is a hotspot…
RT @drkaanyl: Kenarda dursun bu güzel bilgiler, daha çok konuşacağız belli ki... #coronavirus
RT @genperisi: #Covid19 dun paylastigim virus ORF8 bolgesi delesyonu (parca eksilmesi) ve olasi daha hafif seyir hipotezi ORF8 is a hotspot…
@JohnBur92158381 @firefoxx66 Its very probable and a overlooked aspect right now. If this holds true then we should welcome this new variant instead of letting burn out: https://t.co/1Fj0QdKIEi https://t.co/6c106RU585
@c_drosten Die stop codon Mutation auf Protein ORF8 sollte zu einer Inaktivierung desselben führen. Lt. einer Studie sind Varianten ohne aktives ORF8 wohl deutlich weniger gefährlich. Das wären tolle Neuigkeiten: zwar infektiöser, aber viel weniger schwere
RT @genperisi: #Covid19 dun paylastigim virus ORF8 bolgesi delesyonu (parca eksilmesi) ve olasi daha hafif seyir hipotezi ORF8 is a hotspot…
RT @drkaanyl: Kenarda dursun bu güzel bilgiler, daha çok konuşacağız belli ki... #coronavirus
Her şeyin bir sonu vardır ♾
Kenarda dursun bu güzel bilgiler, daha çok konuşacağız belli ki... #coronavirus
@gsgs2 @Jack40071147 @kakape Think this is the paper referenced. https://t.co/6cYxBnxcPf
B.1.1.7 has lost Orf8 which was good news in a Singapore variant. https://t.co/SsLvxsRDLD
#Covid19 dun paylastigim virus ORF8 bolgesi delesyonu (parca eksilmesi) ve olasi daha hafif seyir hipotezi ORF8 is a hotspot for coronavirus mutation. 1. Singapur https://t.co/s3Li2qAagK. +
RT @mikolaj_kam: @nmaliszewski Dlaczego? Nadreprezentatywność danej mutacji w populacji nie oznacza jeszcze że jest groźniejszy od innych.…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @EricTopol: A genomic deletion of #SARCoV2 associated with mild infections, new @TheLancet https://t.co/S7AUzoRwJM Δ382, in OFR8, a hot…
RT @BallouxFrancois: @PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which…
RT @BallouxFrancois: @PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which…
Fuera de S se observó una mutación ORF8 Q27 que trunca la proteína ORF8. La delecion de ORF8 se asoció con una infección clínica más leve y menos inflamación posterior a la infección en Singapur. https://t.co/8o1SfR7FZH
Tweet on new strain from August. Just gonna leave this here...
Scientists weigh in on new strain of virus that has emerged in England and Denmark
RT @BallouxFrancois: @PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which…
@Karl_Lauterbach Relevant sind aber auch die Mutationen in ORF8. Aus früheren Studien z.B aus Singapur ist bekannt, dass Deletionen im ORF8 Gen zu milderen Infektionen führen. Ähnlich wird wohl ORF8 in der UK Variante seine Funktion verloren haben. https:
RT @BallouxFrancois: @PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which…
@c_drosten Mutationen in ORF8 sind ja schon früher aufgetreten (z.B. Singapore). Diese Untersuchungen deuten darauf hin, dass Viren ohne ORF8 mildere Infektionen verursachen. https://t.co/q3Q7ctSRgA
RT @BallouxFrancois: @PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which…
@PaulDenbigh It would be great if the new lineages caused milder symptoms. The UK strain has a deletion in ORF8, which is the only mutation that has been previously associated with less severe symptoms. That said, the evidence is not super-strong at this s
RT @BrianRWasik: Evolutionary theory of infectious diseases suggests that virulence may evolve for lower lethality in a *long generational…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
RT @BallouxFrancois: So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associa…
So far we know of only one type of mutations in #SARSCoV2 that may be associated to milder symptoms, (and none associated to worse symptoms). Deletions in the ORF8 gene have been associated with reduced symptom severity in a study from Singapore 2/ https:/
RT @BangoBilly: @neiljmcevoy @PteRead @Celt46123799 @Jason_Humphreys LOCKDOWN IMPEDES THIS NATURAL WEAKENING NOBEL LAUREATE SCIENCE PRIZE…
@arambaut @sophiegryseels @KurtadikarKetan @LauringLab @EvolveDotZoo @nbierne @firefoxx66 ahh, wait .... one of the mutations makes a stop-codon in ORF8, so that could be good see : https://t.co/bwUUHN98MR
RT @BangoBilly: @heatherawwood VERY well said Doc Wood.... and >> "LOCKDOWN IMPEDES THIS NATURAL WEAKENING" NOBEL LAUREATE SCIENCE PRIZ…
RT @BangoBilly: @Stat_O_Guy "LOCKDOWN IMPEDES THIS NATURAL WEAKENING" NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT ===…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @carpe_diem0820: SARS-CoV-2遺伝子のORF8領域に382ヌクレオチド欠失を有する変異体をシンガポールで1/22-3/21間に、患者29/131例(22%)で確認 当該患者は酸素需要率が低い Effects of a major deletion…
RT @BangoBilly: @ProfKarolSikora NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @BangoBilly: @ProfKarolSikora NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @EFundamentalist: More evidence that lockdowns have made things worse. https://t.co/UhSl3bJ0Iu
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
@MattHancock @MichaelYeadon3
RT @BangoBilly: @allisonpearson NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
More evidence that lockdowns have made things worse.
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @BangoBilly: @allisonpearson NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @BangoBilly: @talkRADIO @JuliaHB1 @S_Hammond NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @BangoBilly: @talkRADIO @JuliaHB1 @S_Hammond NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @BangoBilly: @talkRADIO @JuliaHB1 @S_Hammond NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @BangoBilly: @talkRADIO @JuliaHB1 @S_Hammond NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…
RT @BangoBilly: @talkRADIO @JuliaHB1 @S_Hammond NOBEL LAUREATE SCIENCE PRIZE WINNER === PROFESSOR MICHAEL LEVITT === https://t.co/W0IJtbTZbn
RT @MLevitt_NP2013: Is SARS-CoV-2 mutating to be less lethal? @TheLancet says so https://t.co/m0nkSYBuay. Was told this happens by the viro…