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Animal Cell Technology: From Target to Market

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Cover of 'Animal Cell Technology: From Target to Market'

Table of Contents

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    Book Overview
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    Chapter 1 In Vitro Testing of a New Substance with Anti-Tumor Activity on Mammalian Cells Using Flow Cytometry
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    Chapter 2 Destabilization of Green Fluorescent Protein by Substitution of Its Amino-Terminal Residue
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    Chapter 3 Anti-Tumor Activity of Noguchi Catalyser 21™, a Mineral Water Containing Natural Leaf Soil
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    Chapter 4 Fermented Milk, Kefram-Kefir Enhances Glucose Uptake into Insulin-Responsive Muscle Cells
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    Chapter 5 Optimization of Medium for M2 (Anti-Flag) Hybridoma Using Factorial Matrix Designs
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    Chapter 6 Neurite Outgrowth Promoting Substance from a Marine Alga, Sargassum Macrocarpum
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    Chapter 7 Neutralization of the Biological Activity of Glycosylated and Non-Glycosylated hGM-CSF by Monoclonal Antibodies
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    Chapter 8 High Cell Density Cultivation of Mast Cells in Fluidized-Bed and Fixed-Bed Bioreactors
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    Chapter 9 Over-Expression of Protein Kinase Bα Enhances Recombinant Protein Expression in Transient Systems
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    Chapter 10 100 Liter Transient Transfection
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    Chapter 11 Application of Alphavirus Vectors in Drug Discovery
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    Chapter 12 The Use of UCOE Vectors in Combination with a Preadapted Serum Free, Suspension Cell Line Allows for Rapid Production of Large Quantities of Protein
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    Chapter 13 Overexpression of a Transcription Factor to Maximize Glycoprotein Production in an Inducible Expression System
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    Chapter 14 Glucose Dehydrogenase as Detector Protein of Recombinant Fusion-Proteins Directly in SDS Gels
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    Chapter 15 Successful Transfection of Partially Purified DNA in the HEK293EBNA Cell Line for Transient Expression
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    Chapter 16 Capillary-Aided Cell Cloning
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    Chapter 17 The Comparative Study of Cultural and Productive Characteristics of Different Recombinant Cell Lines Producing Human Erythropoietin
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    Chapter 18 The Use of a C-FOS-GFP Reporter System for Monitoring Apoptosis of Animal Cells Induced by Exotoxins of Pseudomonas Aeruginosa
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    Chapter 19 High Performance Transient Expression in Mammalian Cells
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    Chapter 20 In 30 Days from Plasmid to Product: Expression of a Secreted Fusion Protein Using Hek293-EBNA Cells
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    Chapter 21 SF9 Cells Infection and Fuc-TIII Quality in Serum-Free and Serum-Containing Media
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    Chapter 22 Rapid Expression of Recombinant Proteins in Modified CHO Cells Using the Baculovirus System
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    Chapter 23 Recombinant Glycoprotein Production by CHO Cells in Low Protein Serum Free Medium
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    Chapter 24 Arginine Is a Limiting Essential Amino Acid in Batch Cultures of Recombinant Chinese Hamster Orvary Cells Producing Thrombopoietin
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    Chapter 25 Production of Recombinant Allergen Proder P 1 by CHO Cells Adapted to Grow in Serum-Free Suspension
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    Chapter 26 Pilot Scale Production and Purification of a Soluble E-Selectin-IgG Chimeric Protein
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    Chapter 27 Environmental Effects on Cell Physiology and Metabolism: Response to Elevated pC02
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    Chapter 28 Improved Dual-Regulated Expression Systems for Independent Control of Two Different Transgenes
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    Chapter 29 Metabolic Flux Analysis in Mammalian Cells — Network Modelling as an Example for Metabolic Design in Recombinant BHK Cells
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    Chapter 30 Assessment of Keratin Expression and Xenobiotic Metabolism in Cultured Normal and Transformed Human Oral Keratinocytes
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    Chapter 31 Regulation of Cell Cycle and Productivity in NS0 Cells by the Over-Expression of p21CIP1
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    Chapter 32 Loss of Productivity of a Transfectoma in Long-Term Culture: Recovery of Expression
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    Chapter 33 Adaptation and Selection of NSO Myeloma Cell Lines Producing Recombinant Monoclonal Antibodies in Protein-Free Medium
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    Chapter 34 Specific Effects of Synthetic Oligopeptides in Animal Cell Culture
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    Chapter 35 Differential Enhancement of Monoclonal Antibody Production by Retinoids in Human Hybridomas
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    Chapter 36 Regulation Mechanisms of Antibody Production from Human PBMC Immunized in vitro
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    Chapter 37 Influences of Glutamine Concentration on Cellular Metabolism in Continuous Culture of Hybridoma
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    Chapter 38 Study of NS0 Cell Line Metabolism in Lipid Supplemented Protein Free Media
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    Chapter 39 Metabolic Shifts in Hybridoma Cells Utilising Wheat Peptides
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    Chapter 40 Bi-Phasic Culture Strategies Based on Medium Formulation: Substitution of Glucose by Galactose in CHO Culture
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    Chapter 41 New Advanced Protein-Free, Animal Component-Free Medium for Recombinant Protein Expression in Adherent CHO Cell Cultures
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    Chapter 42 Na+ Is Responsible for Intra-Run Variations of Specific Productivity of CHO Cell Lines Producing Human Anti Rh D IgG in Bioreactors
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    Chapter 43 The Influence of pH on Cell Growth and Specific Productivity of Two CHO Cell Lines Producing Human Anti Rh D IgG
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    Chapter 44 The Modification of a Serum-Free Media Formulation for the Production of Reovirus and the Growth of Vero, MRC-5, MDCK and BHK Cell Lines
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    Chapter 45 The Role of Vitamins in Cell Culture Media
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    Chapter 46 Effect of Sodium Butyrate on Glycosylation of Recombinant Erythropoietin
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    Chapter 47 Identification of Betacellulin as a Major Growth Factor in Foetal Bovine Serum and Development of a Recombinant Betacellulin Analogue for Use in Serum-Free Cell Culture
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    Chapter 48 Monitoring Growth and Death of Vero Cells Cultivated in Bioreactor with Serum-Containing and Serum-Free Media
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    Chapter 49 Effects of a Rice Protein Hydrolysate on Growth of CHO Cells and Production of Human Interferon-γ in a Serum-Free Medium
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    Chapter 50 Suppressive Effect of Electrolyzed-Reduced Water on the Growth of Cancer Cells and Microorganisms
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    Chapter 51 Transient Bcl-x L Overexpression Has Different Effects on Protein Production in Various CHO-Derived Cell Lines
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    Chapter 52 Proteolytic Potential during Batch Cultivation in Serum Free Media of an IFN-γ Producing CHO Cell Line
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    Chapter 53 Genetic Strategies for Apoptosis Protection of Hybridoma Cells Based on Overexpression of Cellular and Viral Proteins
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    Chapter 54 Modulation of Cell Proliferation by Metabolic Engineering
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    Chapter 55 S-Phase Synchronized CHO Cells Show Elevated Transfection Efficiency and Expression Using CA/PO4
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    Chapter 56 Expression of Yeast Pyruvate Carboxylate in hGM-CSF-Producing CHO Cells
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    Chapter 57 The Influence of Culture Conditions on the Development of Trans-Epithelial Electrical Resistance (TEER) and the Junctional Complex of MDCK Cells
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    Chapter 58 Bioreactor for Pharmaceutical Screening Generally Applicable for Primary Cells
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    Chapter 59 Increasing Population of Amniotic Epithelial Cells
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    Chapter 60 Evaluation of the Biological Activity of Some Hormones, Growth Factors and Drugs on Cultured Cells, Isolated from Animal and Human Reproductive Organs
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    Chapter 61 Cultivation of Human Articular Chondrocytes for Autologous Transplantation
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    Chapter 62 A Cell Culture System from the Eye Stalk of Penaeus Indicus
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    Chapter 63 Cytotoxicity of Pyrethroid Insecticides in Rat Hepatoma-Derived Fa32 Cells
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    Chapter 64 New Technologies for Automated Cell Counting Based on Optical Image Analysis “The Cellscreen”
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    Chapter 65 Application of an Acceleration-Stat to Study Insect Cell Metabolism
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    Chapter 66 Factorial Design and Analysis for Rapid Development of an Antibody Production Process in CHO Cells
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    Chapter 67 Development of a Large Scale Process for the Production of Recombinant Truncated Factor VIII in CHO Cells under Cell Growth Arrest Conditions
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    Chapter 68 Continuous Perfusion versus Discontinuous Fed-Batch
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    Chapter 69 The Use of Hydrocyclones for Mammalian Cell Retention in Perfusion Bioreactors
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    Chapter 70 High Throughput Cultivation of Animal Cells Using Shaken Microplate Techniques
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    Chapter 71 Continuous Isolation of rFVIII from Mammalian Cell Culture
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    Chapter 72 Sodium Butyrate Treatment: A Study of Critical Parameters Using CHO Cell Lines Expressing the Green Fluorescent Protein
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    Chapter 73 Development of a Robust Protocol for the Production of Recombinant Proteins up to 20-L Scale Using BEVS
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    Chapter 74 Optimising the Production of a Nuclear Receptor in SF9 Cells Using Response Surface Analysis
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    Chapter 75 Growth of High-Five™ Cells on Cultispher-S Microbarriers
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    Chapter 76 Catching the Wave: The BEVS and the Biowave
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    Chapter 77 Physiology of Insect Cells Cultured in a New Serum-Free Medium
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    Chapter 78 Characterisation and Evaluation of a New Screening System for Animal Cell Culture
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    Chapter 79 Development of Bioprocess Concepts on Vaccine Production: Influenza Virus as an Example
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    Chapter 80 Assay of Serum and Animal Protein Free Media for the Production of a Veterinary Rabies Vaccine by BHK-21 Cells
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    Chapter 81 Cell Cultivation System on the Basis of Porous Ceramic for the Production of Virus-Like Particles
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    Chapter 82 Influence of Cell Culture Media on Adhesion of Animal Cells on Microcarriers
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    Chapter 83 Comparison of Three Different Serum Free Media: Scale up of a Semi-Continuous CHO Cell Process in an Industrial Application
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    Chapter 84 Use of Plant Peptone-Containing Serum-Free Media for the Cultivation of CHO Cells in Suspension and on Microcarriers
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    Chapter 85 Application of Protein-Free Cell Culture Media for the Manufacturing of Biopharmaceuticals
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    Chapter 86 Fluid Bed Granulation as an Alternative to Milled Powders to Improve Performance of Dry-Form, Serum-Free Nutrient Media
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    Chapter 87 NanoColloids: A New Method for Solubilization of Lipophilic Substances Used in Cell Culture
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    Chapter 88 Development and Validation of a Novel Process for the Production of Powdered Cell Culture Media
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    Chapter 89 Separation of Mammalian Cells Using a Specially Designed Rotating Disc Filter
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    Chapter 90 Comparison of Fluidised Bed and Ultrasonic Cell-Retention Systems for High Cell Density Mammalian Cell Culture
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    Chapter 91 Ultrasonic Cell Separation — Production of Monoclonal Antibodies in Continuous Perfusion Cultures
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    Chapter 92 Increased Production Yields of Native Interferon-γ in Membrane Bioreactors by Continuous Harvest
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    Chapter 93 Production of rhEPO in Hollow Fibers’ Bioreactor
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    Chapter 94 Production of rhEPO under Variants of Cultivation Media
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    Chapter 95 Solution to the high Dissolved CO2 Problem in High-Density Perfusion Culture of Mammalian Cells
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    Chapter 96 Perfusion Cell Culture in Disposable Bioreactors
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    Chapter 97 Process Development in a Packed Bed Bioreactor
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    Chapter 98 The Art & Science of Micro-Sparging in High-Density Perfusion Cultures of Animal Cells
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    Chapter 99 Culture of the CB.Hep-1 Hybridoma Using Different in vitro Systems
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    Chapter 100 Selection of Suitable Anti-rHBsAg Mabs for in vitro Production
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    Chapter 101 Reorganizing of Monoclonal Antibodies Process in the Era of Human Genome Cloning
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    Chapter 102 Production of a Highly Pure Mab from Cell-Pharm System CP-2500
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    Chapter 103 How Does Protein Free Medium Turbodoma™ HP-I Perform in Mouse Hybridoma Cultures in Different Culture Systems?
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    Chapter 104 Effect of Seed Cell Density on Specific Growth Rate Using CHO Cells as Model
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    Chapter 105 Adaptation and Growth Kinetics of the Universal Host CHO Cell Lines in Serum-Free Medium
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    Chapter 106 Process Development for Functional Membrane Receptor Production in Mammalian Cells
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    Chapter 107 Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells
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    Chapter 108 The One Step Inoculation Concept: A New Seed-Train Expansion for Recombinant Mammalian Cell Lines
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    Chapter 109 In-Situ Microscopy for On-Line and In-Line Monitoring of Cell Populations in Bioreactors
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    Chapter 110 Measurement of the Viable Cell Density: Validation and Integration of On-Line and Off-Line Capacitance Biomass Monitors for Cell Culture Processes
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    Chapter 111 Robot Automation of Sampling and Sample Management during Cultivation of Mammalian Cells in Pilot Scale
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    Chapter 112 Rapid Estimation of Human Monoclonal Antibody (IgG4) Concentration in Cell Culture Supernatants
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    Chapter 113 Use of Ion-Exchange Membrane Adsorbers for Production of Biopharmaceuticals
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    Chapter 114 Pharmaceuticals Produced by Biotechnology: Quality and Safety Issues
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    Chapter 115 Factory IQ/OQ, A New Approach for Streamlining Validation of Cell Culture Equipment
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    Chapter 116 Critical Issues for the Use of Tangential Flow Filtration Systems for Cell Harvesting Applications
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    Chapter 117 A General Method for the On-Line RT-PCR Detection of Retrovirus Contamination in Cell Lines Used for Protein and Viral Vector Production
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    Chapter 118 Novel Assay for Protein Impurities in Biopharmaceuticals Based on Fluorescence Intensity Distribution Analysis (FIDA)
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    Chapter 119 Development of Mammalian Cell Bioreactor Processes
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    Chapter 120 Development of Microgranulated Form of the Live Measles Vaccine
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    Chapter 121 Bioprocess Development for the Cultivation of Human T-Lymphocytes
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    Chapter 122 Adenovirally Modified Dendritic Cells for Immunotherapy: From Basic Development to Clinical Application
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    Chapter 123 GMP Compliant Expansion of Hematopoietic Stem Cells (CD34+) Selected from Cord Blood for a Phase I Cell Therapy Trial
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    Chapter 124 Multi-Plasmid Vaccines for HIV-1: Issues and Advancements
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    Chapter 125 Continuous Retroviral Vector Production in a Perfusion Bioreactor System
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    Chapter 126 Monolayer and Suspension Cultures of HEK 293 Cells for Recombinant Adenovirus Production for Gene Therapy: Effect of “Cell Passage Number”
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    Chapter 127 Possible Strategies for the Production of Viral Vector: The Role of Engineering Design
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    Chapter 128 Establishing Novel Hepatoma Cell Line for Bioartificial Liver
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    Chapter 129 An Improved Oxygenation Hollow Fiber Bioreactor for the Cultivation of Liver Cells
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    Chapter 130 Medium for Gene Therapy: Improved Protein-Free Media for Growth and Production of Viral Vectors for Use in Gene Therapy
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    Chapter 131 Induction of a T Helper Cell Response against the Tumor Associated Antigen Her-2 Using Monocyte-Derived Dendritic Cells
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    Chapter 132 Cultivation of Human HCMV Specific Lymphocytes — An Example for Adoptive Immunotherapy
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    Chapter 133 Application of hTERT Promoter to Cancer Therapy
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    Chapter 134 Establishment of a Genetic System to Coordinate Feeder Cell Growth in Cocultures with Primary Cells
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    Chapter 135 Construction and Operation of a Bioreactor for Three-Dimensional Cartilage-Implants
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    Chapter 136 Tissue Engineering of Meniscal Cartilage
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    Chapter 137 Anti-Oxidative Water Improves Diabetes
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    Chapter 138 Effect of Transfection-Induced Changes in Expression of Insulin-Like Growth Factor Binding Proteins on Secretory Activity and Responses of Ovarian Cell Cultures
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    Chapter 139 Cultivation of Primary Osteogenic Cells in Serum-Reduced or Serum-Free Culture Media: Attachment, Proliferation and Differentiation
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Title
Animal Cell Technology: From Target to Market
Published by
Springer Netherlands, January 2001
DOI 10.1007/978-94-010-0369-8
ISBNs
978-9-40-103897-3, 978-9-40-100369-8
Editors

Dr Elisabeth Lindner-Olsson, Ms Nathalie Chatzissavidou, Dr Elke Lüllau

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 25%
Student > Master 3 19%
Student > Ph. D. Student 3 19%
Other 2 13%
Student > Doctoral Student 2 13%
Other 2 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 50%
Chemical Engineering 3 19%
Biochemistry, Genetics and Molecular Biology 3 19%
Medicine and Dentistry 1 6%
Unknown 1 6%