Chapter title |
Helicobacter pylori, Cancer, and the Gastric Microbiota.
|
---|---|
Chapter number | 19 |
Book title |
Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
|
Published in |
Advances in experimental medicine and biology, August 2016
|
DOI | 10.1007/978-3-319-41388-4_19 |
Pubmed ID | |
Book ISBNs |
978-3-31-941386-0, 978-3-31-941388-4
|
Authors |
Lydia E. Wroblewski, Richard M. Peek Jr., Richard M. Peek, Wroblewski, Lydia E., Peek, Richard M. |
Editors |
Marnix Jansen, Nicholas A. Wright |
Abstract |
Gastric adenocarcinoma is one of the leading causes of cancer-related death worldwide and Helicobacter pylori infection is the strongest known risk factor for this disease. Although the stomach was once thought to be a sterile environment, it is now known to house many bacterial species leading to a complex interplay between H. pylori and other residents of the gastric microbiota. In addition to the role of H. pylori virulence factors, host genetic polymorphisms, and diet, it is now becoming clear that components of the gastrointestinal microbiota may also influence H. pylori-induced pathogenesis. In this chapter, we discuss emerging data regarding the gastric microbiota in humans and animal models and alterations that occur to the composition of the gastric microbiota in the presence of H. pylori infection that may augment the risk of developing gastric cancer. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Unknown | 105 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 11% |
Student > Ph. D. Student | 12 | 11% |
Student > Bachelor | 9 | 8% |
Student > Doctoral Student | 7 | 7% |
Researcher | 7 | 7% |
Other | 13 | 12% |
Unknown | 46 | 43% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 16 | 15% |
Medicine and Dentistry | 15 | 14% |
Biochemistry, Genetics and Molecular Biology | 15 | 14% |
Agricultural and Biological Sciences | 5 | 5% |
Nursing and Health Professions | 2 | 2% |
Other | 7 | 7% |
Unknown | 46 | 43% |