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Antibody Engineering

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Cover of 'Antibody Engineering'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody Design and Humanization via In Silico Modeling
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    Chapter 2 Antibody Affinity Maturation by Computational Design
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    Chapter 3 Use of IMGT® Databases and Tools for Antibody Engineering and Humanization
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    Chapter 4 Construction of Human Naïve Antibody Gene Libraries
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    Chapter 5 Construction of Synthetic Antibody Libraries
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    Chapter 6 Construction of Histidine-Enriched Shark IgNAR Variable Domain Antibody Libraries for the Isolation of pH-Sensitive vNAR Fragments
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    Chapter 7 Display Technologies for Generation of Ig Single Variable Domains
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    Chapter 8 A Streamlined Approach for the Construction of Large Yeast Surface Display Fab Antibody Libraries
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    Chapter 9 Phage Display and Selections on Purified Antigens
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    Chapter 10 Selection of Antibodies to Transiently Expressed Membrane Proteins Using Phage Display
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    Chapter 11 Selection of Antibody Fragments Against Structured DNA by Phage Display
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    Chapter 12 Selection of Antibody Fragments by Yeast Display
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    Chapter 13 Rapid Selection of High-Affinity Antibody scFv Fragments Using Ribosome Display
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    Chapter 14 In Vitro Selection of Single-Domain Antibody (VHH) Using cDNA Display
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    Chapter 15 Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood
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    Chapter 16 Expression of IgG Monoclonals with Engineered Immune Effector Functions
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    Chapter 17 An IRES-Mediated Tricistronic Vector for Efficient Generation of Stable, High-Level Monoclonal Antibody Producing CHO DG44 Cell Lines
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    Chapter 18 Production, Purification, and Characterization of Antibody-TNF Superfamily Ligand Fusion Proteins
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    Chapter 19 Chemoenzymatic Defucosylation of Therapeutic Antibodies for Enhanced Effector Functions Using Bacterial α-Fucosidases
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    Chapter 20 Fc Glyco- and Fc Protein-Engineering: Design of Antibody Variants with Improved ADCC and CDC Activity
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    Chapter 21 Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High-Affinity Interaction with FcRn at pH 6.0
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    Chapter 22 Measuring Antibody-Antigen Binding Kinetics Using Surface Plasmon Resonance
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    Chapter 23 Parallel Evolution of Antibody Affinity and Thermal Stability for Optimal Biotherapeutic Development
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    Chapter 24 The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies
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    Chapter 25 Selection and Use of Intracellular Antibodies
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    Chapter 26 Site-Specific Radioactive Labeling of Nanobodies
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Title
Antibody Engineering
Published by
Springer New York, January 2018
DOI 10.1007/978-1-4939-8648-4
ISBNs
978-1-4939-8647-7, 978-1-4939-8648-4
Editors

Damien Nevoltris, Patrick Chames

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X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 28%
Researcher 5 17%
Student > Master 4 14%
Student > Bachelor 3 10%
Other 1 3%
Other 4 14%
Unknown 4 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 48%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Agricultural and Biological Sciences 2 7%
Medicine and Dentistry 2 7%
Immunology and Microbiology 1 3%
Other 3 10%
Unknown 5 17%