Chapter title |
Short Overview
|
---|---|
Chapter number | 38 |
Book title |
Mitophagy
|
Published in |
Methods in molecular biology, May 2017
|
DOI | 10.1007/7651_2017_38 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7749-9, 978-1-4939-7750-5
|
Authors |
Norihiko Furuya, Furuya, Norihiko |
Abstract |
Mitochondrial autophagy (mitophagy) is a mitochondrial quality control mechanism that selectively removes damaged mitochondria via autophagic degradation. Autophagic adaptor/receptor proteins contribute to the selective degradation of damaged mitochondria by autophagy. A part of them containing both ubiquitin binding domains and Atg8 interacting motif (AIM)/LC3 interacting region (LIR) motifs, which bind to the autophagy-related protein 8 (Atg8) family (LC3 and GABARAP family), lead ubiquitylated (damaged) mitochondria to selective removal. On the other hand, some specific outer mitochondrial membrane-anchored proteins containing AIM/LIR motif function as another type of autophagy adaptor/receptor proteins. Here I briefly summarize mechanisms of mitophagy and its related proteins. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 29% |
Student > Master | 5 | 24% |
Student > Doctoral Student | 2 | 10% |
Professor | 2 | 10% |
Researcher | 2 | 10% |
Other | 2 | 10% |
Unknown | 2 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 14% |
Engineering | 2 | 10% |
Energy | 2 | 10% |
Business, Management and Accounting | 1 | 5% |
Computer Science | 1 | 5% |
Other | 9 | 43% |
Unknown | 3 | 14% |