| Chapter title |
Monitoring of Iron Depletion-Induced Mitophagy in Pathogenic Yeast
|
|---|---|
| Chapter number | 40 |
| Book title |
Mitophagy
|
| Published in |
Methods in molecular biology, May 2017
|
| DOI | 10.1007/7651_2017_40 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7749-9, 978-1-4939-7750-5
|
| Authors |
Tanabe, Koichi, Nagi, Minoru, Koichi Tanabe, Minoru Nagi |
| Abstract |
Mitophagy, which is the degradation of mitochondria via selective autophagic machinery, is thought to be involved in regulating the mass and function of mitochondria. Methods for detection of mitophagy have been reported for several fungal cells including some budding yeast, methylotrophic yeast, and filamentous fungi. Mitophagy in Saccharomyces cerevisiae is activated under nitrogen-poor conditions; however, the regulatory mechanism of mitophagy in most fungi has not been elucidated. Here we describe methods to monitor mitophagy in the pathogenic yeast Candida glabrata under iron-depleted conditions but not under nitrogen starvation. This observation may provide some clues to elucidate the physiological roles of mitophagy in eukaryotes. |
X Demographics
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|---|---|---|
| France | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 50% |
| Researcher | 1 | 25% |
| Other | 1 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 50% |
| Agricultural and Biological Sciences | 2 | 50% |