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Imaging Mass Spectrometry

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Cover of 'Imaging Mass Spectrometry'

Table of Contents

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    Book Overview
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    Chapter 1 “A Future Amalgamation Between the Scientist and the Clinician?”
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    Chapter 2 Fresh Frozen Versus Formalin-Fixed Paraffin Embedded for Mass Spectrometry Imaging
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    Chapter 3 Imaging MS of Rodent Ocular Tissues and the Optic Nerve
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    Chapter 4 MALDI-MSI of Lipids in Human Skin
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    Chapter 5 MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer
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    Chapter 6 Droplet-Based Liquid Extraction for Spatially-Resolved Microproteomics Analysis of Tissue Sections
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    Chapter 7 DESI Mass Spectrometry Imaging (MSI)
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    Chapter 8 Peptide Imaging: Maximizing Peptide Yield, Optimization of the “Peptide Mass Fingerprint”
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    Chapter 9 MALDI-MS Imaging in the Study of Glomerulonephritis
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    Chapter 10 Hierarchical Cluster Analysis to Aid Diagnostic Image Data Visualization of MS and Other Medical Imaging Modalities
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    Chapter 11 Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant Metabolites
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    Chapter 12 Mass Spectrometry Imaging of Drugs of Abuse in Hair
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    Chapter 13 MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks
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    Chapter 14 ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections
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    Chapter 15 Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
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    Chapter 16 The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues, and the Way Forward
Attention for Chapter 7: DESI Mass Spectrometry Imaging (MSI)
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Chapter title
DESI Mass Spectrometry Imaging (MSI)
Chapter number 7
Book title
Imaging Mass Spectrometry
Published in
Methods in molecular biology, May 2017
DOI 10.1007/978-1-4939-7051-3_7
Pubmed ID
Book ISBNs
978-1-4939-7050-6, 978-1-4939-7051-3
Authors

Emmanuelle Claude, Emrys A. Jones, Steven D. Pringle

Editors

Laura M. Cole

Abstract

Desorption Electrospray Ionization (DESI) mass spectrometry is a technique that allows chemical information to be obtained directly from a wide range of surfaces. Using a 2D stage, DESI can be implemented in an imaging mode whereby MS spectra are collected by rastering the spray across the whole surface. Here, we describe the implementation and optimization of DESI imaging for metabolites and lipids from tissue sections using oa-TOF mass spectrometers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 16%
Student > Ph. D. Student 7 14%
Researcher 7 14%
Student > Master 6 12%
Professor > Associate Professor 1 2%
Other 0 0%
Unknown 22 43%
Readers by discipline Count As %
Chemistry 11 22%
Biochemistry, Genetics and Molecular Biology 6 12%
Immunology and Microbiology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Environmental Science 1 2%
Other 3 6%
Unknown 26 51%