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Imaging Mass Spectrometry

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Cover of 'Imaging Mass Spectrometry'

Table of Contents

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    Book Overview
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    Chapter 1 “A Future Amalgamation Between the Scientist and the Clinician?”
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    Chapter 2 Fresh Frozen Versus Formalin-Fixed Paraffin Embedded for Mass Spectrometry Imaging
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    Chapter 3 Imaging MS of Rodent Ocular Tissues and the Optic Nerve
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    Chapter 4 MALDI-MSI of Lipids in Human Skin
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    Chapter 5 MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer
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    Chapter 6 Droplet-Based Liquid Extraction for Spatially-Resolved Microproteomics Analysis of Tissue Sections
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    Chapter 7 DESI Mass Spectrometry Imaging (MSI)
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    Chapter 8 Peptide Imaging: Maximizing Peptide Yield, Optimization of the “Peptide Mass Fingerprint”
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    Chapter 9 MALDI-MS Imaging in the Study of Glomerulonephritis
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    Chapter 10 Hierarchical Cluster Analysis to Aid Diagnostic Image Data Visualization of MS and Other Medical Imaging Modalities
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    Chapter 11 Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant Metabolites
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    Chapter 12 Mass Spectrometry Imaging of Drugs of Abuse in Hair
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    Chapter 13 MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks
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    Chapter 14 ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections
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    Chapter 15 Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
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    Chapter 16 The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues, and the Way Forward
Attention for Chapter 15: Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
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Chapter title
Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
Chapter number 15
Book title
Imaging Mass Spectrometry
Published in
Methods in molecular biology, May 2017
DOI 10.1007/978-1-4939-7051-3_15
Pubmed ID
Book ISBNs
978-1-4939-7050-6, 978-1-4939-7051-3
Authors

Paul J. Trim

Editors

Laura M. Cole

Abstract

Here, we describe a method for obtaining whole-body MALDI imaging data. MALDI imaging provides chemical compound-specific information not attainable with conventional histology techniques. The specificity of mass spectrometry with the addition of spatial information makes this a very powerful technique, especially for the analysis of endogenous and exogenous small molecules. This chapter will provide the reader with a comprehensive description of the techniques involved in obtaining high-quality MALDI mass spectrometry imaging (MSI) data from large tissue sections.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 50%
Unknown 1 50%
Readers by discipline Count As %
Economics, Econometrics and Finance 1 50%
Unknown 1 50%