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Mendeley readers
| Chapter title |
Red Blood Cells: A Source of Extracellular Vesicles
|
|---|---|
| Chapter number | 2 |
| Book title |
Extracellular Vesicles
|
| Published in |
Methods in molecular biology, January 2017
|
| DOI | 10.1007/978-1-4939-7253-1_2 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7251-7, 978-1-4939-7253-1
|
| Authors |
Winston Patrick Kuo, John C. Tigges, Vasilis Toxavidis, Ionita Ghiran |
| Abstract |
During their lifetime, like all other cell types, red blood cells (RBCs) release both exosomes and plasma membrane derived EVs (ectosomes). RBC exosomes are formed only during the development of RBCs in bone marrow, and are released following the fusion of microvesicular bodies (MVB) with the plasma membrane. On the other hand, RBC EVs are generated during normal aging of RBCs in circulation by budding of the plasma membrane due to complement -mediated calcium influx, followed by vesicle shedding. This makes red blood cells and stored red cells a reliable source of EVs for basic and clinical research. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 16% |
| Researcher | 7 | 11% |
| Student > Postgraduate | 5 | 8% |
| Student > Master | 5 | 8% |
| Student > Doctoral Student | 4 | 6% |
| Other | 8 | 13% |
| Unknown | 24 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 25% |
| Agricultural and Biological Sciences | 7 | 11% |
| Medicine and Dentistry | 4 | 6% |
| Immunology and Microbiology | 3 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 27 | 43% |