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Chapter title |
NMDA Receptors as Voltage Sensors
|
---|---|
Chapter number | 16 |
Book title |
NMDA Receptors
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7321-7_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7320-0, 978-1-4939-7321-7
|
Authors |
Roustem Khazipov |
Abstract |
The membrane potential is an essential parameter of a living cell. However, measurements of the membrane potential using conventional techniques are associated with a number of artifacts. Cell-attached recordings of the currents through NMDA receptor channels enable noninvasive measurements of the neuronal membrane potential. This approach overcomes the problem of a leak conductance introduced during intracellular sharp electrode recordings and whole-cell patch-clamp recordings. Here, we describe the procedures of using cell-attached recordings of NMDA receptor channels to measure the true membrane potential. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 1 | 20% |
Other | 1 | 20% |
Unknown | 3 | 60% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 1 | 20% |
Physics and Astronomy | 1 | 20% |
Neuroscience | 1 | 20% |
Unknown | 2 | 40% |