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Mendeley readers
Chapter title |
Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing
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Chapter number | 23 |
Book title |
Genome Instability
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Published in |
Methods in molecular biology, January 2018
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DOI | 10.1007/978-1-4939-7306-4_23 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7305-7, 978-1-4939-7306-4
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Authors |
Clinton D. Orebaugh, Scott A. Lujan, Adam B. Burkholder, Anders R. Clausen, Thomas A. Kunkel |
Abstract |
Ribonucleotides embedded within DNA render the DNA sensitive to the formation of single-stranded breaks under alkali conditions. Here, we describe a next-generation sequencing method called hydrolytic end sequencing (HydEn-seq) to map ribonucleotides inserted into the genome of Saccharomyce cerevisiae strains deficient in ribonucleotide excision repair. We use this method to map several genomic features in wild-type and replicase variant yeast strains. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 2 | 22% |
Researcher | 2 | 22% |
Student > Ph. D. Student | 1 | 11% |
Other | 1 | 11% |
Professor | 1 | 11% |
Other | 1 | 11% |
Unknown | 1 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 44% |
Agricultural and Biological Sciences | 2 | 22% |
Nursing and Health Professions | 1 | 11% |
Chemistry | 1 | 11% |
Unknown | 1 | 11% |