| Chapter title |
Gut Microbiota and Bone Health
|
|---|---|
| Chapter number | 4 |
| Book title |
Understanding the Gut-Bone Signaling Axis
|
| Published in |
Advances in experimental medicine and biology, November 2017
|
| DOI | 10.1007/978-3-319-66653-2_4 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-966651-8, 978-3-31-966653-2
|
| Authors |
Darin Quach, Robert A. Britton, Quach, Darin, Britton, Robert A. |
| Abstract |
The past decade has seen an explosion of research in the area of how the bacteria that inhabit the human body impact health and disease. One of the more surprising concepts to emerge from this work is the ability of the intestinal microbiota to impact virtually all systems in the body. Recently, the role of gut bacteria in bone health and disease has received more significant attention. In this chapter, we review what has been learned about how the gut microbiome impacts bone health and discuss possible mechanisms of how the gut-bone axis may be connected. We also discuss the use of therapeutic microbes in the modulation of bone health. Finally, we propose an emerging field of the gut-brain-bone axis, in which the gut drives bone physiology via regulation of key hormones that are originally synthesized in the brain. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 8% |
| India | 1 | 8% |
| Spain | 1 | 8% |
| United States | 1 | 8% |
| Unknown | 9 | 69% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 85% |
| Scientists | 2 | 15% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 70 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 14% |
| Student > Bachelor | 8 | 11% |
| Student > Master | 7 | 10% |
| Student > Doctoral Student | 6 | 9% |
| Student > Ph. D. Student | 5 | 7% |
| Other | 16 | 23% |
| Unknown | 18 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 19% |
| Biochemistry, Genetics and Molecular Biology | 8 | 11% |
| Medicine and Dentistry | 5 | 7% |
| Nursing and Health Professions | 3 | 4% |
| Immunology and Microbiology | 3 | 4% |
| Other | 13 | 19% |
| Unknown | 25 | 36% |