Chapter title |
Immunology of Gut-Bone Signaling
|
---|---|
Chapter number | 5 |
Book title |
Understanding the Gut-Bone Signaling Axis
|
Published in |
Advances in experimental medicine and biology, November 2017
|
DOI | 10.1007/978-3-319-66653-2_5 |
Pubmed ID | |
Book ISBNs |
978-3-31-966651-8, 978-3-31-966653-2
|
Authors |
Fraser L. Collins, Jonathan D. Schepper, Naiomy Deliz Rios-Arce, Michael D. Steury, Ho Jun Kang, Heather Mallin, Daniel Schoenherr, Glen Camfield, Saima Chishti, Laura R. McCabe, Narayanan Parameswaran |
Abstract |
In recent years a link between the gastrointestinal tract and bone health has started to gain significant attention. Dysbiosis of the intestinal microbiota has been linked to the pathology of a number of diseases which are associated with bone loss. In addition modulation of the intestinal microbiota with probiotic bacteria has revealed to have both beneficial local and systemic effects. In the present chapter, we discuss the intestinal and bone immune systems, explore how intestinal disease affects the immune system, and examine how these pathologic changes could adversely impact bone health. |
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Mendeley readers
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Other | 4 | 14% |
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