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Cancer Systems Biology

Overview of attention for book
Cover of 'Cancer Systems Biology'

Table of Contents

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    Book Overview
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    Chapter 1 Detection of Combinatorial Mutational Patterns in Human Cancer Genomes by Exclusivity Analysis
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    Chapter 2 Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data
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    Chapter 3 Analyzing DNA Methylation Patterns During Tumor Evolution
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    Chapter 4 MicroRNA Networks in Breast Cancer Cells
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    Chapter 5 Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels
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    Chapter 6 Phosphoproteomics-Based Profiling of Kinase Activities in Cancer Cells
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    Chapter 7 Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research
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    Chapter 8 Quantitative Analysis of Tyrosine Kinase Signaling Across Differentially Embedded Human Glioblastoma Tumors
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    Chapter 9 Prediction of Clinical Endpoints in Breast Cancer Using NMR Metabolic Profiles
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    Chapter 10 Stochastic and Deterministic Models for the Metastatic Emission Process: Formalisms and Crosslinks
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    Chapter 11 Mechanically Coupled Reaction-Diffusion Model to Predict Glioma Growth: Methodological Details
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    Chapter 12 Profiling Tumor Infiltrating Immune Cells with CIBERSORT
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    Chapter 13 Systems Biology Approaches in Cancer Pathology
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    Chapter 14 Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing
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    Chapter 15 A Robust Optimization Approach to Cancer Treatment under Toxicity Uncertainty
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    Chapter 16 Modeling of Interactions between Cancer Stem Cells and their Microenvironment: Predicting Clinical Response
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    Chapter 17 Methods for High-throughput Drug Combination Screening and Synergy Scoring
Attention for Chapter 11: Mechanically Coupled Reaction-Diffusion Model to Predict Glioma Growth: Methodological Details
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Chapter title
Mechanically Coupled Reaction-Diffusion Model to Predict Glioma Growth: Methodological Details
Chapter number 11
Book title
Cancer Systems Biology
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7493-1_11
Pubmed ID
Book ISBNs
978-1-4939-7492-4, 978-1-4939-7493-1
Authors

David A. HormuthII, Stephanie L. Eldridge, Jared A. Weis, Michael I. Miga, Thomas E. Yankeelov, David A. Hormuth

Abstract

Biophysical models designed to predict the growth and response of tumors to treatment have the potential to become a valuable tool for clinicians in care of cancer patients. Specifically, individualized tumor forecasts could be used to predict response or resistance early in the course of treatment, thereby providing an opportunity for treatment selection or adaption. This chapter discusses an experimental and modeling framework in which noninvasive imaging data is used to initialize and parameterize a subject-specific model of tumor growth. This modeling approach is applied to an analysis of murine models of glioma growth.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 26%
Student > Bachelor 4 17%
Student > Postgraduate 3 13%
Student > Doctoral Student 1 4%
Researcher 1 4%
Other 1 4%
Unknown 7 30%
Readers by discipline Count As %
Mathematics 6 26%
Engineering 4 17%
Physics and Astronomy 2 9%
Medicine and Dentistry 2 9%
Computer Science 1 4%
Other 2 9%
Unknown 6 26%