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Population Epigenetics

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Attention for Chapter 268: 5-Hydroxymethylcytosine Profiling in Human DNA.
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Chapter title
5-Hydroxymethylcytosine Profiling in Human DNA.
Chapter number 268
Book title
Population Epigenetics
Published in
Methods in molecular biology, July 2015
DOI 10.1007/7651_2015_268
Pubmed ID
Book ISBNs
978-1-4939-6901-2, 978-1-4939-6903-6
Authors

Thomson, John P, Nestor, Colm E, Meehan, Richard R, John P. Thomson, Colm E. Nestor, Richard R. Meehan, Thomson, John P., Nestor, Colm E., Meehan, Richard R.

Abstract

Since its "re-discovery" in 2009, there has been significant interest in defining the genome-wide distribution of DNA marked by 5-hydroxymethylation at cytosine bases (5hmC). In recent years, technological advances have resulted in a multitude of unique strategies to map 5hmC across the human genome. Here we discuss the wide range of approaches available to map this modification and describe in detail the affinity based methods which result in the enrichment of 5hmC marked DNA for downstream analysis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor 1 20%
Student > Ph. D. Student 1 20%
Researcher 1 20%
Unknown 2 40%
Readers by discipline Count As %
Environmental Science 1 20%
Pharmacology, Toxicology and Pharmaceutical Science 1 20%
Medicine and Dentistry 1 20%
Unknown 2 40%