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Mendeley readers
| Chapter title |
Non-targeted Identification of d-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS
|
|---|---|
| Chapter number | 7 |
| Book title |
Peptidomics
|
| Published by |
Humana Press, New York, NY, February 2018
|
| DOI | 10.1007/978-1-4939-7537-2_7 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7536-5, 978-1-4939-7537-2
|
| Authors |
Hua-Chia Tai, James W. Checco, Jonathan V. Sweedler |
| Abstract |
D-Amino acid-containing peptides (DAACPs) in animals are a class of bioactive molecules formed via the posttranslational modification of peptides consisting of all-L-amino acid residues. Amino acid residue isomerization greatly impacts the function of the resulting DAACP. However, because isomerization does not change the peptide's mass, this modification is difficult to detect by most mass spectrometry-based peptidomic approaches. Here we describe a method for the identification of DAACPs that can be used to systematically survey peptides extracted from a tissue sample in a non-targeted manner. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 2 | 22% |
| Student > Doctoral Student | 1 | 11% |
| Professor | 1 | 11% |
| Student > Ph. D. Student | 1 | 11% |
| Researcher | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 3 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 3 | 33% |
| Biochemistry, Genetics and Molecular Biology | 2 | 22% |
| Environmental Science | 1 | 11% |
| Unknown | 3 | 33% |