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Mammalian Transient Receptor Potential (TRP) Cation Channels

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Cover of 'Mammalian Transient Receptor Potential (TRP) Cation Channels'

Table of Contents

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    Book Overview
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    Chapter 1 TRP Channels and Thermosensation
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    Chapter 2 TRPs in Mechanosensing and Volume Regulation
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    Chapter 3 TRPs as Chemosensors (ROS, RNS, RCS, Gasotransmitters)
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    Chapter 4 Photosensitive TRPs.
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    Chapter 5 TRPs in Taste and Chemesthesis
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    Chapter 6 TRPs and Pain.
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    Chapter 7 TRPs in Hearing.
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    Chapter 8 TRPs in Olfaction
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    Chapter 9 Evolutionarily Conserved, Multitasking TRP Channels: Lessons from Worms and Flies
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    Chapter 10 Structural Biology of TRP Channels
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    Chapter 11 High-Resolution Views of TRPV1 and Their Implications for the TRP Channel Superfamily
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    Chapter 12 Physiological Functions and Regulation of TRPC Channels
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    Chapter 13 The TRPCs–STIM1–Orai Interaction
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    Chapter 14 The TRPC Family of TRP Channels: Roles Inferred (Mostly) from Knockout Mice and Relationship to ORAI Proteins
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    Chapter 15 TRPs: Modulation by Drug-Like Compounds
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    Chapter 16 TRP Channels in Reproductive (Neuro)Endocrinology
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    Chapter 17 Modulation of TRP Ion Channels by Venomous Toxins
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    Chapter 18 Phosphoinositide Regulation of TRP Channels
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    Chapter 19 TRP Modulation by Natural Compounds
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    Chapter 20 What Do We Really Know and What Do We Need to Know: Some Controversies, Perspectives, and Surprises
Attention for Chapter 7: TRPs in Hearing.
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Chapter title
TRPs in Hearing.
Chapter number 7
Book title
Mammalian Transient Receptor Potential (TRP) Cation Channels
Published in
Handbook of experimental pharmacology, January 2014
DOI 10.1007/978-3-319-05161-1_7
Pubmed ID
Book ISBNs
978-3-31-905160-4, 978-3-31-905161-1
Authors

Damiano Zanini, Martin C Göpfert, Martin C. Göpfert

Abstract

Hearing is a particularly sensitive form of mechanosensation that relies on dedicated ion channels transducing sound-induced vibrations that hardly exceed Brownian motion. Attempts to molecularly identify these auditory transduction channels have put the focus on TRPs in ears. In Drosophila, hearing has been shown to involve TRPA, TRPC, TRPN, and TRPV subfamily members, with candidate auditory transduction channels including NOMPC (=TRPN1) and the TRPVs Nan and Iav. In vertebrates, TRPs are unlikely to form auditory transduction channels, yet most TRPs are expressed in inner ear tissues, and mutations in TRPN1, TRPVA1, TRPML3, TRPV4, and TRPC3/TRPC6 have been implicated in inner ear function. Starting with a brief introduction of fly and vertebrate auditory anatomies and transduction mechanisms, this review summarizes our current understanding of the auditory roles of TRPs.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 23%
Researcher 3 14%
Professor 3 14%
Student > Postgraduate 2 9%
Student > Doctoral Student 2 9%
Other 5 23%
Unknown 2 9%
Readers by discipline Count As %
Neuroscience 6 27%
Agricultural and Biological Sciences 6 27%
Biochemistry, Genetics and Molecular Biology 5 23%
Medicine and Dentistry 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 0 0%
Unknown 3 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2014.
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#3,209,527
of 4,018,593 outputs
Outputs from Handbook of experimental pharmacology
#145
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Outputs of similar age
#78,554
of 99,040 outputs
Outputs of similar age from Handbook of experimental pharmacology
#2
of 2 outputs
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