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PTEN

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Attention for Chapter 17: C. elegans Methods to Study PTEN
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Chapter title
C. elegans Methods to Study PTEN
Chapter number 17
Book title
PTEN
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3299-3_17
Pubmed ID
Book ISBNs
978-1-4939-3297-9, 978-1-4939-3299-3
Authors

Shanqing Zheng, Ian D. Chin-Sang

Abstract

C. elegans encodes a PTEN homolog called DAF-18 and human PTEN can functionally replace DAF-18. Thus C. elegans provides a valuable model organism to study PTEN. This chapter provides methods to study DAF-18/PTEN function in C. elegans. We provide methods to genotype daf-18/Pten mutants, visualize and quantify DAF-18/PTEN in C. elegans, as well as to study physiological and developmental processes that will provide molecular insight on DAF-18/PTEN function.

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Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 33%
Other 1 33%
Student > Master 1 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 67%
Medicine and Dentistry 1 33%