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Mendeley readers
| Chapter title |
Lipoplexes Strengthened by Anionic Polymers: Easy Preparation of Highly Effective siRNA Vectors Based on Cationic Lipids and Anionic Polymers
|
|---|---|
| Chapter number | 8 |
| Book title |
Non-Viral Gene Delivery Vectors
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3718-9_8 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3716-5, 978-1-4939-3718-9
|
| Authors |
Danielle Campiol Arruda, Anne Schlegel, Pascal Bigey, Virginie Escriou |
| Abstract |
RNA interference is an invaluable tool in biology to specifically silence a given gene. Synthetic duplexes of RNA oligonucleotides are widely used to induce mRNA degradation in cultured cells or in whole organisms. They have to be vectorized to reach their target site. Here, we describe the preparation of highly efficient siRNA vectors based on cationic liposomes and polyanionic polymers and their application in cultured cells to silence reporter and/or endogenous genes. |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 36% |
| Student > Bachelor | 2 | 18% |
| Researcher | 2 | 18% |
| Student > Doctoral Student | 2 | 18% |
| Unknown | 1 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 27% |
| Medicine and Dentistry | 2 | 18% |
| Chemistry | 2 | 18% |
| Chemical Engineering | 1 | 9% |
| Unknown | 3 | 27% |