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Ligand-Macromolecular Interactions in Drug Discovery

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Cover of 'Ligand-Macromolecular Interactions in Drug Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 An Historical Overview of Drug Discovery
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    Chapter 2 Ligand Macromolecule Interactions: Theoretical Principles of Molecular Recognition
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    Chapter 3 X-ray crystallography in drug discovery.
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    Chapter 4 Virtual Screening of Compound Libraries
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    Chapter 5 Combinatorial Chemistry and the Synthesis of Compound Libraries
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    Chapter 6 Ligand-Based Nuclear Magnetic Resonance Screening Techniques
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    Chapter 7 Isothermal Titration Calorimetry and Differential Scanning Calorimetry
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    Chapter 8 Adaptive Combinatorial Design of Focused Compound Libraries
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    Chapter 9 Chemical Microarrays: A New Tool for Discovery Enzyme Inhibitors
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    Chapter 10 Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer Techniques for PI3K Assays
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    Chapter 11 Small Molecule Protein Interaction Profiling with Functional Protein Microarrays
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    Chapter 12 Capillary Electrophoresis in Drug Discovery
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    Chapter 13 SPR in Drug Discovery: Searching Bioactive Compounds in Plant Extracts
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    Chapter 14 Application of Frontal Affinity Chromatography with Mass Spectrometry (FAC–MS) for Stereospecific Ligand–Macromolecule Interaction, Detection and Screening
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    Chapter 15 GPC Spin Column HPLC–ESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins
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    Chapter 16 A scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening.
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    Chapter 17 A Natural Products Approach to Drug Discovery: Probing Modes of Action of Antitumor Agents by Genome-Scale cDNA Library Screening
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    Chapter 18 Ligand–Macromolecule Interactions in Live Cells by Fluorescence Correlation Spectroscopy
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Citations

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Title
Ligand-Macromolecular Interactions in Drug Discovery
Published by
Humana Press, August 2010
DOI 10.1007/978-1-60761-244-5
ISBNs
978-1-60761-243-8, 978-1-60761-244-5
Editors

Roque, Ana Cecília A.

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 109 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 4%
Student > Ph. D. Student 2 2%
Student > Postgraduate 1 <1%
Unknown 102 94%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Agricultural and Biological Sciences 1 <1%
Biochemistry, Genetics and Molecular Biology 1 <1%
Psychology 1 <1%
Chemistry 1 <1%
Other 0 0%
Unknown 102 94%