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Mendeley readers
| Chapter title |
Studying the Early Stages of Protein Aggregation Using Replica Exchange Molecular Dynamics Simulations
|
|---|---|
| Chapter number | 15 |
| Book title |
Protein Amyloid Aggregation
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-2978-8_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-2977-1, 978-1-4939-2978-8
|
| Authors |
Joan-Emma Shea, Zachary A. Levine |
| Abstract |
The simulation of protein aggregation poses several computational challenges due to the disparate time and lengths scales that are involved. This chapter focuses on the use of atomistically detailed simulations to probe the initial steps of aggregation, with an emphasis on the Tau peptide as a model system, run under a replica exchange molecular dynamics protocol. |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 50% |
| Researcher | 2 | 17% |
| Unspecified | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Unknown | 2 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 4 | 33% |
| Biochemistry, Genetics and Molecular Biology | 2 | 17% |
| Chemical Engineering | 1 | 8% |
| Unspecified | 1 | 8% |
| Neuroscience | 1 | 8% |
| Other | 1 | 8% |
| Unknown | 2 | 17% |