Mechanisms of Bacterial Colonization of Implants and Host Response.
A Modern Approach to Biofilm-Related Orthopaedic Implant Infections
Advances in experimental medicine and biology, January 2016
Christof Wagner, G. Maria Hänsch
The review focuses on the current knowledge and the most pertinent hypotheses regarding the local host immune response as the key factor for the pathogenesis of implant-associated infections. Although bacterial biofilms have long been recognized as causative agents, the link between the infection and the devastating inflammatory response, particularly the localized tissue destruction and bone degradation is less well understood. Understanding these consequences of infection, however, is of utmost importance, because suppressing inflammation and preventing bone destruction could be a novel, alternative therapeutic option in cases when eradicating the infections fails.
|Readers by professional status||Count||As %|
|Student > Ph. D. Student||5||42%|
|Student > Doctoral Student||1||8%|
|Student > Bachelor||1||8%|
|Student > Master||1||8%|
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|Medicine and Dentistry||5||42%|
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