↓ Skip to main content

A Modern Approach to Biofilm-Related Orthopaedic Implant Infections

Overview of attention for book
Attention for Chapter 154: Microbiological Diagnosis of Implant-Related Infections: Scientific Evidence and Cost/Benefit Analysis of Routine Antibiofilm Processing
Altmetric Badge

Citations

dimensions_citation
1 Dimensions

Readers on

mendeley
25 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Microbiological Diagnosis of Implant-Related Infections: Scientific Evidence and Cost/Benefit Analysis of Routine Antibiofilm Processing
Chapter number 154
Book title
A Modern Approach to Biofilm-Related Orthopaedic Implant Infections
Published in
Advances in experimental medicine and biology, January 2016
DOI 10.1007/5584_2016_154
Pubmed ID
Book ISBNs
978-3-31-952273-9, 978-3-31-952274-6
Authors

Lorenzo Drago, Elena De Vecchi

Abstract

Prosthetic joint infection is one of the most severe complication following joint arthroplasty, producing a significant worsening of patient's quality of life. Management of PJIs requires extended courses of antimicrobial therapy, multiple surgical interventions and prolonged hospital stay, with a consequent economic burden, which is thought to markedly increase in the next years due to the expected burden in total joint arthroplasties. The present review summarizes the present knowledge on microbiological diagnosis of prosthetic joint infections, focusing on aethiological agents and discussing pros and cons of the available strategies for their diagnosis.Intra-operative clinical diagnosis and pathogen identification is considered the diagnostic benchmark, however the presence of bacterial biofilm makes pathogen detection with traditional microbiological techniques highly ineffective. Diagnosis of PJIs is a rather complex challenge for orthopedics and requires a strict collaboration between different specialists: orthopaedics, infectivologists, microbiologists, pathologists and radiologists. Diagnostic criteria have been described by national and international association and scientific societies. Clinicians should be trained on how to use it, but more importantly they should know potential and limitation of the available tests in order to use them appropriately.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 24%
Student > Ph. D. Student 5 20%
Student > Doctoral Student 3 12%
Other 2 8%
Researcher 1 4%
Other 1 4%
Unknown 7 28%
Readers by discipline Count As %
Medicine and Dentistry 8 32%
Immunology and Microbiology 3 12%
Sports and Recreations 1 4%
Nursing and Health Professions 1 4%
Physics and Astronomy 1 4%
Other 1 4%
Unknown 10 40%