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Antibody-Drug Conjugates

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Cover of 'Antibody-Drug Conjugates'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody-Drug Conjugate (ADC) Clinical Pipeline: A Review.
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    Chapter 2 Antibody–Drug Conjugate Target Selection: Critical Factors
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    Chapter 3 Selecting an Optimal Antibody for Antibody–Drug Conjugate Therapy: Internalization and Intracellular Localization
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    Chapter 4 Antibody–Drug Conjugate Payloads
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    Chapter 5 Linker Technologies for Antibody–Drug Conjugates
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    Chapter 6 In Vivo Testing of Drug-Linker Stability
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    Chapter 7 Pharmacokinetics and ADME Characterizations of Antibody–Drug Conjugates
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    Chapter 8 Safe Handling of Cytotoxic Compounds in a Biopharmaceutical Environment
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    Chapter 9 Micro- and Mid-Scale Maleimide-Based Conjugation of Cytotoxic Drugs to Antibody Hinge Region Thiols for Tumor Targeting
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    Chapter 10 Protocols for Lysine Conjugation
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    Chapter 11 Engineering THIOMABs for Site-Specific Conjugation of Thiol-Reactive Linkers.
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    Chapter 12 Enzymatic antibody modification by bacterial transglutaminase.
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    Chapter 13 Formulation development of antibody-drug conjugates.
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    Chapter 14 Conjugation Process Development and Scale-Up
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    Chapter 15 Methods for Conjugating Antibodies to Nanocarriers
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    Chapter 16 Drug-to-Antibody Ratio (DAR) by UV/Vis Spectroscopy
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    Chapter 17 Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by Hydrophobic Interaction Chromatography and Reversed Phase High-Performance Liquid Chromatography
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    Chapter 18 Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by LC-ESI-MS
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    Chapter 19 Determination of Charge Heterogeneity and Level of Unconjugated Antibody by Imaged cIEF
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    Chapter 20 Risk-Based Scientific Approach for Determination of Extractables/Leachables from Biomanufacturing of Antibody–Drug Conjugates (ADCs)
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Citations

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Title
Antibody-Drug Conjugates
Published by
Humana Press, August 2013
DOI 10.1007/978-1-62703-541-5
ISBNs
978-1-62703-540-8, 978-1-62703-541-5
Editors

Ducry, Laurent

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 33%
Student > Ph. D. Student 4 19%
Researcher 3 14%
Other 2 10%
Student > Doctoral Student 1 5%
Other 2 10%
Unknown 2 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 38%
Chemistry 4 19%
Agricultural and Biological Sciences 2 10%
Immunology and Microbiology 1 5%
Neuroscience 1 5%
Other 2 10%
Unknown 3 14%