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Antibody-Drug Conjugates

Overview of attention for book
Cover of 'Antibody-Drug Conjugates'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody-Drug Conjugate (ADC) Clinical Pipeline: A Review.
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    Chapter 2 Antibody–Drug Conjugate Target Selection: Critical Factors
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    Chapter 3 Selecting an Optimal Antibody for Antibody–Drug Conjugate Therapy: Internalization and Intracellular Localization
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    Chapter 4 Antibody–Drug Conjugate Payloads
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    Chapter 5 Linker Technologies for Antibody–Drug Conjugates
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    Chapter 6 In Vivo Testing of Drug-Linker Stability
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    Chapter 7 Pharmacokinetics and ADME Characterizations of Antibody–Drug Conjugates
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    Chapter 8 Safe Handling of Cytotoxic Compounds in a Biopharmaceutical Environment
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    Chapter 9 Micro- and Mid-Scale Maleimide-Based Conjugation of Cytotoxic Drugs to Antibody Hinge Region Thiols for Tumor Targeting
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    Chapter 10 Protocols for Lysine Conjugation
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    Chapter 11 Engineering THIOMABs for Site-Specific Conjugation of Thiol-Reactive Linkers.
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    Chapter 12 Enzymatic antibody modification by bacterial transglutaminase.
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    Chapter 13 Formulation development of antibody-drug conjugates.
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    Chapter 14 Conjugation Process Development and Scale-Up
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    Chapter 15 Methods for Conjugating Antibodies to Nanocarriers
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    Chapter 16 Drug-to-Antibody Ratio (DAR) by UV/Vis Spectroscopy
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    Chapter 17 Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by Hydrophobic Interaction Chromatography and Reversed Phase High-Performance Liquid Chromatography
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    Chapter 18 Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by LC-ESI-MS
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    Chapter 19 Determination of Charge Heterogeneity and Level of Unconjugated Antibody by Imaged cIEF
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    Chapter 20 Risk-Based Scientific Approach for Determination of Extractables/Leachables from Biomanufacturing of Antibody–Drug Conjugates (ADCs)
Attention for Chapter 17: Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by Hydrophobic Interaction Chromatography and Reversed Phase High-Performance Liquid Chromatography
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
patent
1 patent

Citations

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44 Dimensions

Readers on

mendeley
125 Mendeley
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Chapter title
Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by Hydrophobic Interaction Chromatography and Reversed Phase High-Performance Liquid Chromatography
Chapter number 17
Book title
Antibody-Drug Conjugates
Published in
Methods in molecular biology, January 2013
DOI 10.1007/978-1-62703-541-5_17
Pubmed ID
Book ISBNs
978-1-62703-540-8, 978-1-62703-541-5
Authors

Jun Ouyang, Ouyang, Jun

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 125 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 31 25%
Student > Ph. D. Student 31 25%
Student > Master 14 11%
Student > Bachelor 11 9%
Other 8 6%
Other 12 10%
Unknown 18 14%
Readers by discipline Count As %
Chemistry 30 24%
Biochemistry, Genetics and Molecular Biology 25 20%
Agricultural and Biological Sciences 14 11%
Pharmacology, Toxicology and Pharmaceutical Science 14 11%
Chemical Engineering 5 4%
Other 17 14%
Unknown 20 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2021.
All research outputs
#2,979,028
of 23,045,021 outputs
Outputs from Methods in molecular biology
#597
of 13,194 outputs
Outputs of similar age
#31,431
of 282,288 outputs
Outputs of similar age from Methods in molecular biology
#25
of 340 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,194 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,288 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 340 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.