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Cancer Cytogenetics

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Cover of 'Cancer Cytogenetics'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Cancer Cytogenetics: An Introduction.
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    Chapter 2 Chromosome Preparation for Myeloid Malignancies.
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    Chapter 3 Chromosome Preparation for Acute Lymphoblastic Leukemia.
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    Chapter 4 Chromosome Preparation for Chronic Lymphoid Malignancies.
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    Chapter 5 Cytogenetic Harvesting of Cancer Cells and Cell Lines.
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    Chapter 6 Chromosome Bandings.
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    Chapter 7 Chromosome Recognition.
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    Chapter 8 Applications of Fluorescence In Situ Hybridization Technology in Malignancies.
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    Chapter 9 Fluorescence In Situ Hybridization Probe Preparation.
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    Chapter 10 Fluorescence In Situ Hybridization Probe Validation for Clinical Use.
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    Chapter 11 Fluorescence In Situ Hybridization on Tissue Sections.
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    Chapter 12 Cytoplasmic Immunoglobulin Light Chain Revelation and Interphase Fluorescence In Situ Hybridization in Myeloma.
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    Chapter 13 Quantitative Fluorescence In Situ Hybridization (QFISH).
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    Chapter 14 High Resolution Fiber-Fluorescence In Situ Hybridization.
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    Chapter 15 Array-Based Comparative Genomic Hybridization (aCGH).
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    Chapter 16 Multicolor Karyotyping and Fluorescence In Situ Hybridization-Banding (MCB/mBAND).
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    Chapter 17 Cytogenetics for Biological Dosimetry.
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    Chapter 18 Recurrent Cytogenetic Abnormalities in Myelodysplastic Syndromes.
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    Chapter 19 Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia.
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    Chapter 20 Recurrent Cytogenetic Abnormalities in Myeloproliferative Neoplasms and Chronic Myeloid Leukemia.
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    Chapter 21 Recurrent Cytogenetic Abnormalities in Acute Lymphoblastic Leukemia.
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    Chapter 22 Recurrent Cytogenetic Abnormalities in Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia.
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    Chapter 23 Recurrent Cytogenetic Abnormalities in Multiple Myeloma.
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    Chapter 24 Cytogenetic Nomenclature and Reporting.
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    Chapter 25 Cytogenetic Resources and Information.
Attention for Chapter 14: High Resolution Fiber-Fluorescence In Situ Hybridization.
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Chapter title
High Resolution Fiber-Fluorescence In Situ Hybridization.
Chapter number 14
Book title
Cancer Cytogenetics
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6703-2_14
Pubmed ID
Book ISBNs
978-1-4939-6701-8, 978-1-4939-6703-2
Authors

Christine J. Ye, Henry H. Heng, Ye, Christine J., Heng, Henry H.

Editors

Thomas S.K. Wan

Abstract

High resolution fiber-Fluorescence in situ hybridization (FISH) is an advanced FISH technology that can effectively bridge the resolution gap between probe hybridizing on DNA molecules and chromosomal regions. Since various types of DNA and chromatin fibers can be generated reflecting different degrees of DNA/chromatin packaging status, fiber-FISH technology has been successfully used in diverse molecular cytogenetic/cytogenomic studies. Following a brief review of this technology, including its major development and increasing applications, typical protocols to generate DNA/chromatin fiber will be described, coupled with rationales, as well as technical tips. These released DNA/chromatin fibers are suitable for an array of cytogenetic/cytogenomic analyses.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Lecturer > Senior Lecturer 1 14%
Student > Ph. D. Student 1 14%
Student > Bachelor 1 14%
Researcher 1 14%
Unknown 3 43%
Readers by discipline Count As %
Chemistry 2 29%
Medicine and Dentistry 1 14%
Biochemistry, Genetics and Molecular Biology 1 14%
Unknown 3 43%