| Chapter title |
The Human Stomach in Health and Disease: Infection Strategies by Helicobacter pylori
|
|---|---|
| Chapter number | 1 |
| Book title |
Molecular Pathogenesis and Signal Transduction by Helicobacter pylori
|
| Published in |
Current topics in microbiology and immunology, January 2017
|
| DOI | 10.1007/978-3-319-50520-6_1 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-950519-0, 978-3-31-950520-6
|
| Authors |
Karen Robinson, Darren P. Letley, Kazuyo Kaneko |
| Editors |
Nicole Tegtmeyer, Steffen Backert |
| Abstract |
Helicobacter pylori is a bacterial pathogen which commonly colonizes the human gastric mucosa from early childhood and persists throughout life. In the vast majority of cases, the infection is asymptomatic. H. pylori is the leading cause of peptic ulcer disease and gastric cancer, however, and these outcomes occur in 10-15% of those infected. Gastric adenocarcinoma is the third most common cause of cancer-associated death, and peptic ulcer disease is a significant cause of morbidity. Disease risk is related to the interplay of numerous bacterial host and environmental factors, many of which influence chronic inflammation and damage to the gastric mucosa. This chapter summarizes what is known about health and disease in H. pylori infection, and highlights the need for additional research in this area. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 48 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 12% |
| Student > Bachelor | 5 | 10% |
| Researcher | 4 | 8% |
| Professor > Associate Professor | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 5 | 10% |
| Unknown | 21 | 43% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 14% |
| Medicine and Dentistry | 6 | 12% |
| Immunology and Microbiology | 6 | 12% |
| Agricultural and Biological Sciences | 3 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 22 | 45% |