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Mendeley readers
| Chapter title |
Use of a Fluorescent Substrate to Measure ACE2 Activity in the Mouse Abdominal Aorta
|
|---|---|
| Chapter number | 5 |
| Book title |
The Renin-Angiotensin-Aldosterone System
|
| Published in |
Methods in molecular biology, May 2017
|
| DOI | 10.1007/978-1-4939-7030-8_5 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7028-5, 978-1-4939-7030-8
|
| Authors |
Yu Wang, Lisa A. Cassis, Sean E. Thatcher Ph.D., Sean E. Thatcher |
| Editors |
Sean E. Thatcher |
| Abstract |
The use of fluorogenic substrates to measure enzymatic activity is widely used to understand function within different experimental models. ACE2 is important in understanding the balance between AngII and Ang-(1-7) and how this balance could then in turn influence hypertension or other disease outcomes. Here, we describe a method to measure ACE2 activity in abdominal aorta of hyperlipidemic mice under both saline and AngII infusion. |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 40% |
| Professor > Associate Professor | 2 | 20% |
| Other | 1 | 10% |
| Unknown | 3 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 3 | 30% |
| Medicine and Dentistry | 2 | 20% |
| Neuroscience | 1 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
| Unknown | 3 | 30% |