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Chapter title |
A genetic strategy to obtain p-gal4 elements in the Drosophila hox genes.
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Chapter number | 4 |
Book title |
Hox Genes
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Published in |
Methods in molecular biology, January 2014
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DOI | 10.1007/978-1-4939-1242-1_4 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1241-4, 978-1-4939-1242-1
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Authors |
Luis de Navas, David Foronda, Delia Del Saz, Ernesto Sánchez-Herrero, Delia del Saz |
Editors |
Yacine Graba, René Rezsohazy |
Abstract |
The Drosophila Gal4/UAS system allows the expression of any gene of interest in restricted domains. We devised a genetic strategy, based on the P-element replacement and UAS-y (+) techniques, to generate Gal4 lines inserted in Hox genes of Drosophila that are, at the same time, mutant for the resident genes. This makes possible to express different wild-type or mutant Hox proteins in the precise domains of Hox gene expression, and thus to test the functional value of these proteins in mutant rescue experiments. |
Mendeley readers
The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor | 1 | 50% |
Researcher | 1 | 50% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 100% |