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Mendeley readers
| Chapter title |
Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases
|
|---|---|
| Chapter number | 3 |
| Book title |
Phosphodiesterases: CNS Functions and Diseases
|
| Published in |
Advances in neurobiology, January 2017
|
| DOI | 10.1007/978-3-319-58811-7_3 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-958809-4, 978-3-31-958811-7
|
| Authors |
Yafang Hu, Suyue Pan, Han-Ting Zhang |
| Abstract |
Both cyclin-dependent kinase 5 (Cdk5) and cyclic AMP (cAMP)/protein kinase A (PKA) regulate fundamental central nervous system (CNS) functions including neuronal survival, neurite and axonal outgrowth, neuron development and cognition. Cdk5, a serine/threonine kinase, is activated by p35 or p39 and phosphorylates multiple signaling components of various pathways, including cAMP/PKA signaling. Here, we review the recent literature on the interaction between Cdk5 and cAMP/PKA signaling and their role in the mediation of CNS functions and neuropsychiatric and neurodegenerative diseases. |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 15 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 20% |
| Student > Master | 2 | 13% |
| Student > Ph. D. Student | 1 | 7% |
| Lecturer > Senior Lecturer | 1 | 7% |
| Professor > Associate Professor | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 6 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 3 | 20% |
| Agricultural and Biological Sciences | 1 | 7% |
| Biochemistry, Genetics and Molecular Biology | 1 | 7% |
| Psychology | 1 | 7% |
| Chemistry | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 8 | 53% |