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Phosphodiesterases: CNS Functions and Diseases

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Cover of 'Phosphodiesterases: CNS Functions and Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 Phosphodiesterase Diversity and Signal Processing Within cAMP Signaling Networks
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    Chapter 2 Current Understanding of PDE10A in the Modulation of Basal Ganglia Circuitry
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    Chapter 3 Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases
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    Chapter 4 The PDE4 cAMP-Specific Phosphodiesterases: Targets for Drugs with Antidepressant and Memory-Enhancing Action
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    Chapter 5 Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases
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    Chapter 6 From Age-Related Cognitive Decline to Alzheimer’s Disease: A Translational Overview of the Potential Role for Phosphodiesterases
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    Chapter 7 The Past, Present, and Future of Phosphodiesterase-4 Modulation for Age-Induced Memory Loss
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    Chapter 8 A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood
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    Chapter 9 Role of PDE9 in Cognition
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    Chapter 10 Regulation of Striatal Neuron Activity by Cyclic Nucleotide Signaling and Phosphodiesterase Inhibition: Implications for the Treatment of Parkinson’s Disease
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    Chapter 11 Role of Phosphodiesterases in Huntington’s Disease
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    Chapter 12 The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders
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    Chapter 13 Phosphodiesterase 1: A Unique Drug Target for Degenerative Diseases and Cognitive Dysfunction
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    Chapter 14 PDE Inhibitors for the Treatment of Schizophrenia
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    Chapter 15 Targeting Phosphodiesterases in Pharmacotherapy for Substance Dependence
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    Chapter 16 Genetic Understanding of Stroke Treatment: Potential Role for Phosphodiesterase Inhibitors
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    Chapter 17 A Unique Sub-Pocket for Improvement of Selectivity of Phosphodiesterase Inhibitors in CNS
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