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Functional Genomics

Overview of attention for book
Cover of 'Functional Genomics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Predicting RNA Structure with Vfold
  3. Altmetric Badge
    Chapter 2 RNA Function Prediction
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    Chapter 3 Computational Prediction of Novel miRNAs from Genome-Wide Data
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    Chapter 4 Protein Structure Modeling with MODELLER
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    Chapter 5 Protein Function Prediction
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    Chapter 6 Capturing Three-Dimensional Genome Organization in Individual Cells by Single-Cell Hi-C
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    Chapter 7 Genome-Wide Cell Type-Specific Mapping of In Vivo Chromatin Protein Binding Using an FLP-Inducible DamID System in Drosophila
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    Chapter 8 DNA Methylation Profiling Using Long-Read Single Molecule Real-Time Bisulfite Sequencing (SMRT-BS)
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    Chapter 9 Copy Number Variation Analysis by Droplet Digital PCR
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    Chapter 10 MicroScale Thermophoresis: A Rapid and Precise Method to Quantify Protein–Nucleic Acid Interactions in Solution
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    Chapter 11 Establishment of the CRISPR/Cas9 System for Targeted Gene Disruption and Gene Tagging
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    Chapter 12 Holistic and Affordable Analyses of MicroRNA Expression Profiles Using Tagged cDNA Libraries and a Multiplex Sequencing Strategy
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    Chapter 13 MicroRNA Expression Analysis Using Small RNA Sequencing Discovery and RT-qPCR-Based Validation
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    Chapter 14 Using FirePlex™ Particle Technology for Multiplex MicroRNA Profiling Without RNA Purification
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    Chapter 15 Multiplex Real-Time PCR Using Encoded Microparticles for MicroRNA Profiling
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    Chapter 16 Optimized Whole Transcriptome Profiling of Motor Axons
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    Chapter 17 2D-DIGE in Proteomics
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    Chapter 18 STAGE-Diging in Proteomics
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    Chapter 19 Protein Arrays I: Antibody Arrays
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    Chapter 20 Protein Arrays II: Antigen Arrays
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    Chapter 21 Protein Arrays III: Reverse-Phase Protein Arrays
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    Chapter 22 Isolation of Exosomes for the Purpose of Protein Cargo Analysis with the Use of Mass Spectrometry
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    Chapter 23 Virus-Induced Gene Silencing (VIGS) and Foreign Gene Expression in Pisum sativum L. Using the “One-Step” Bean pod mottle virus (BPMV) Viral Vector
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    Chapter 24 Re-expressing Epigenetically Silenced Genes by Inducing DNA Demethylation Through Targeting of Ten-Eleven Translocation 2 to Any Given Genomic Locus
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    Chapter 25 Knockdown of Rice microRNA166 by Short Tandem Target Mimic (STTM)
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    Chapter 26 RNAi-Mediated Knockdown of Protein Expression
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    Chapter 27 Engineered Zinc Finger DNA-Binding Domains: Synthesis, Assessment of DNA-Binding Affinity, and Direct Protein Delivery to Mammalian Cells
  29. Altmetric Badge
    Chapter 28 Production, Purification, and Titration of First-Generation Adenovirus Vectors
Attention for Chapter 4: Protein Structure Modeling with MODELLER
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

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1 news outlet

Citations

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Readers on

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199 Mendeley
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Chapter title
Protein Structure Modeling with MODELLER
Chapter number 4
Book title
Functional Genomics
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-7231-9_4
Pubmed ID
Book ISBNs
978-1-4939-7230-2, 978-1-4939-7231-9
Authors

Benjamin Webb, Andrej Sali, Webb, Benjamin, Sali, Andrej

Abstract

Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized at atomic resolution using experimental structure determination methods. Computational protein structure modeling techniques have the potential to bridge this sequence-structure gap. In the following chapter, we present an example that illustrates the use of MODELLER to construct a comparative model for a protein with unknown structure. Automation of a similar protocol has resulted in models of useful accuracy for domains in more than half of all known protein sequences.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 199 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 199 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 18%
Researcher 28 14%
Student > Master 28 14%
Student > Bachelor 24 12%
Student > Doctoral Student 14 7%
Other 31 16%
Unknown 38 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 71 36%
Agricultural and Biological Sciences 28 14%
Chemistry 12 6%
Pharmacology, Toxicology and Pharmaceutical Science 8 4%
Engineering 6 3%
Other 27 14%
Unknown 47 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2022.
All research outputs
#3,826,294
of 23,005,189 outputs
Outputs from Methods in molecular biology
#974
of 13,159 outputs
Outputs of similar age
#76,493
of 421,224 outputs
Outputs of similar age from Methods in molecular biology
#113
of 1,074 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,159 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,224 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 1,074 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.