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Neurodegenerative Diseases

Overview of attention for book
Cover of 'Neurodegenerative Diseases'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Acuted Disseminated Encephalomyelitis
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    Chapter 2 Age-Related Macular Degeneration
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    Chapter 3 Arachnoid Cysts
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    Chapter 4 Autism Spectrum Disorders: Information for Pediatricians Supporting Families of Young Children on the Spectrum
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    Chapter 5 Autosomal Recessive Charcot-Marie-Tooth Neuropathy
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    Chapter 6 Creutzfeldt-Jakob disease.
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    Chapter 7 Epigenetics in autism and other neurodevelopmental diseases.
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    Chapter 8 Epilepsy and Epileptic Syndrome
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    Chapter 9 Frontotemporal Lobar Degeneration.
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    Chapter 10 Neurodegenerative Diseases
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    Chapter 11 Juvenile Neuronal Ceroid Lipofuscinoses
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    Chapter 12 Neurodegenerative Diseases
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    Chapter 13 Leukodystrophies
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    Chapter 14 Machado-Joseph Disease and other Rare Spinocerebellar Ataxias.
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    Chapter 15 Neurodegenerations induced by organophosphorous compounds.
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    Chapter 16 Mitochondrial Importance in Alzheimer’s, Huntington’s and Parkinson’s Diseases
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    Chapter 17 Multiple sclerosis.
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    Chapter 18 Myotonic Dystrophy Type 1 or Steinert’s Disease
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    Chapter 19 Neurodegeneration in diabetes mellitus.
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    Chapter 20 Neurofibromatoses
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    Chapter 21 Oxidative stress in developmental brain disorders.
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    Chapter 22 Oxidative Stress and Mitochondrial Dysfunction in Down Syndrome
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    Chapter 23 Pick’s Disease
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    Chapter 24 Premature Aging Syndrome
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    Chapter 25 The savant syndrome and its possible relationship to epilepsy.
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    Chapter 26 Sjogren-Larsson Syndrome
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    Chapter 27 The spinocerebellar ataxias: clinical aspects and molecular genetics.
  29. Altmetric Badge
    Chapter 28 Tourette syndrome.
Attention for Chapter 6: Creutzfeldt-Jakob disease.
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1 tweeter


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Chapter title
Creutzfeldt-Jakob disease.
Chapter number 6
Book title
Neurodegenerative Diseases
Published in
Advances in experimental medicine and biology, March 2012
DOI 10.1007/978-1-4614-0653-2_6
Pubmed ID
Book ISBNs
978-1-4614-0652-5, 978-1-4614-0653-2

Sikorska B, Knight R, Ironside JW, Liberski PP, Sikorska, Beata, Knight, Richard, Ironside, James W., Liberski, Paweł P., Beata Sikorska, Richard Knight, James W. Ironside, Paweł P. Liberski


Creutzfeldt-Jakob disease (CJD), a neurodegenerative disorder that is the commonest form of human prion disease or transmissible spongiform encephalopathies (TSEs). Four types of CJD are known: Sporadic (sCJD), familial or genetic (gCJD); iatrogenic (iCJD) and variant CJD (vCJD). The latter results from transmission of bovine spongiform encephalopathy (BSE) from cattle to humans. The combination of PrP(Sc) peptide (either 21 kDa or 19 kDa) and the status of the codon 129 of the gene (PRNP) encoding for PrP (either Methionine or Valine) is used to classify sCJD into 6 types: MM1 and MV1, the most common; VV2; MV2 (Brownell/Oppenheimer syndrome); MM2; VV1 and sporadic fatal insomnia, in that order of prevalence. Genetic CJD is caused by diverse mutations in the PRNP gene. The neuropathology of CJD consists of spongiform change, astro- and microgliosis and poorly defined neuronal loss. In a proportion of cases, amyloid plaques, like those of kuru, are seen. PrP immunohistochemistry reveals different types of PrP(Sc) deposits - the most common is the synaptic-type, but perivacuolar, perineuronal and plaque-like deposits may be also detected.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Spain 1 2%
Ecuador 1 2%
France 1 2%
Unknown 45 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 20%
Researcher 8 16%
Student > Bachelor 8 16%
Student > Master 5 10%
Professor > Associate Professor 2 4%
Other 7 14%
Unknown 10 20%
Readers by discipline Count As %
Medicine and Dentistry 12 24%
Biochemistry, Genetics and Molecular Biology 9 18%
Agricultural and Biological Sciences 8 16%
Neuroscience 6 12%
Social Sciences 1 2%
Other 4 8%
Unknown 10 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2012.
All research outputs
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Outputs from Advances in experimental medicine and biology
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Outputs of similar age
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Outputs of similar age from Advances in experimental medicine and biology
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Altmetric has tracked 11,530,104 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,072 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 105,223 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.