| Chapter title |
Extracellular RNAs: A New Awareness of Old Perspectives
|
|---|---|
| Chapter number | 1 |
| Book title |
Extracellular RNA
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7652-2_1 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7651-5, 978-1-4939-7652-2
|
| Authors |
Noah Sadik, Lilian Cruz, Alessandra Gurtner, Rodosthenis S. Rodosthenous, Sophie A. Dusoswa, Olivia Ziegler, Thomas Sebastiaan Van Solinge, Zhiyun Wei, Ane Miren Salvador-Garicano, Bence Gyorgy, Marike Broekman, Leonora Balaj, Sadik, Noah, Cruz, Lilian, Gurtner, Alessandra, Rodosthenous, Rodosthenis S., Dusoswa, Sophie A., Ziegler, Olivia, Van Solinge, Thomas Sebastiaan, Wei, Zhiyun, Salvador-Garicano, Ane Miren, Gyorgy, Bence, Broekman, Marike, Balaj, Leonora, Solinge, Thomas Sebastiaan |
| Abstract |
Extracellular RNA (exRNA) has recently expanded as a highly important area of study in biomarker discovery and cancer therapeutics. exRNA consists of diverse RNA subpopulations that are normally protected from degradation by incorporation into membranous vesicles or by lipid/protein association. They are found circulating in biofluids, and have proven highly promising for minimally invasive diagnostic and prognostic purposes, particularly in oncology. Recent work has made progress in our understanding of exRNAs-from their biogenesis, compartmentalization, and vesicle packaging to their various applications as biomarkers and therapeutics, as well as the new challenges that arise in isolation and purification for accurate and reproducible analysis. Here we review the most recent advancements in exRNA research. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Slovenia | 1 | 20% |
| United Kingdom | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 102 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 17% |
| Researcher | 14 | 14% |
| Student > Master | 12 | 12% |
| Student > Bachelor | 6 | 6% |
| Student > Doctoral Student | 4 | 4% |
| Other | 15 | 15% |
| Unknown | 34 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 30 | 29% |
| Agricultural and Biological Sciences | 11 | 11% |
| Medicine and Dentistry | 8 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Engineering | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 40 | 39% |