Chapter title |
Tumor-Derived Microparticles to Monitor Colorectal Cancer Evolution
|
---|---|
Chapter number | 17 |
Book title |
Colorectal Cancer
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7765-9_17 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7764-2, 978-1-4939-7765-9
|
Authors |
Diane Mege, Laurence Panicot-Dubois, Christophe Dubois |
Abstract |
Colorectal cancer is the most common gastrointestinal cancer and the second-most common cause of cancer-related death worldwide. Microparticles are small vesicles known to be implicated in tumor growth, the development of metastases, and cancer-associated procoagulant activity. We have reported a specific hallmark of microparticles in colorectal and pancreatic cancers, the so-called "microparticulosome." We have also reported on variations in the microparticulosome in the case of the occurrence of a thromboembolic event. Here, we describe our flow cytometry-based methods for identifying and characterizing tumor-derived microparticles and thereby monitoring colorectal cancer evolution. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 2 | 18% |
Student > Master | 2 | 18% |
Researcher | 1 | 9% |
Unknown | 6 | 55% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 18% |
Medicine and Dentistry | 2 | 18% |
Agricultural and Biological Sciences | 1 | 9% |
Unknown | 6 | 55% |