Chapter title |
Chromatin Structure of Epstein-Barr Virus Latent Episomes.
|
---|---|
Chapter number | 5 |
Book title |
Epstein Barr Virus Volume 1
|
Published in |
Current topics in microbiology and immunology, January 2015
|
DOI | 10.1007/978-3-319-22822-8_5 |
Pubmed ID | |
Book ISBNs |
978-3-31-922821-1, 978-3-31-922822-8
|
Authors |
Lieberman, Paul M, Paul M. Lieberman, Lieberman, Paul M. |
Abstract |
EBV latent infection is characterized by a highly restricted pattern of viral gene expression. EBV can establish latent infections in multiple different tissue types with remarkable variation and plasticity in viral transcription and replication. During latency, the viral genome persists as a multi-copy episome, a non-integrated-closed circular DNA with nucleosome structure similar to cellular chromosomes. Chromatin assembly and histone modifications contribute to the regulation of viral gene expression, DNA replication, and episome persistence during latency. This review focuses on how EBV latency is regulated by chromatin and its associated processes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 16% |
Other | 3 | 12% |
Student > Bachelor | 2 | 8% |
Student > Master | 2 | 8% |
Student > Doctoral Student | 1 | 4% |
Other | 5 | 20% |
Unknown | 8 | 32% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 7 | 28% |
Medicine and Dentistry | 7 | 28% |
Neuroscience | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Unknown | 9 | 36% |