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Oncogene-Induced Senescence

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Cover of 'Oncogene-Induced Senescence'

Table of Contents

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    Book Overview
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    Chapter 1 The Immortal Senescence
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    Chapter 2 Senescence Phenotypes Induced by Ras in Primary Cells
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    Chapter 3 Cellular Model of p21-Induced Senescence
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    Chapter 4 Detecting Markers of Therapy-Induced Senescence in Cancer Cells
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    Chapter 5 Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence
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    Chapter 6 Detection of Dysfunctional Telomeres in Oncogene-Induced Senescence
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    Chapter 7 RT-qPCR Detection of Senescence-Associated Circular RNAs
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    Chapter 8 Oncogene-Induced Senescence
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    Chapter 9 Detecting the Senescence-Associated Secretory Phenotype (SASP) by High Content Microscopy Analysis
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    Chapter 10 Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells
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    Chapter 11 Using [U- 13 C 6 ]-Glucose Tracer to Study Metabolic Changes in Oncogene-Induced Senescence Fibroblasts
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    Chapter 12 Detection of the Ubiquitinome in Cells Undergoing Oncogene-Induced Senescence
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    Chapter 13 Detection of Reactive Oxygen Species in Cells Undergoing Oncogene-Induced Senescence
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    Chapter 14 Detection of Senescent Cells by Extracellular Markers Using a Flow Cytometry-Based Approach
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    Chapter 15 Metabolic Changes Investigated by Proton NMR Spectroscopy in Cells Undergoing Oncogene-Induced Senescence
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    Chapter 16 Oncogene-Induced Senescence
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    Chapter 17 Senescence-Like Phenotypes in Human Nevi
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    Chapter 18 Detection of Oncogene-Induced Senescence In Vivo
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    Chapter 19 Detection of Senescence Markers During Mammalian Embryonic Development
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    Chapter 20 Induction and Detection of Oncogene-Induced Cellular Senescence in Drosophila
Attention for Chapter 12: Detection of the Ubiquitinome in Cells Undergoing Oncogene-Induced Senescence
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Chapter title
Detection of the Ubiquitinome in Cells Undergoing Oncogene-Induced Senescence
Chapter number 12
Book title
Oncogene-Induced Senescence
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6670-7_12
Pubmed ID
Book ISBNs
978-1-4939-6668-4, 978-1-4939-6670-7
Authors

Hengrui Zhu, Linh Le, Hsin-Yao Tang, David W. Speicher, Rugang Zhang, Zhu, Hengrui, Le, Linh, Tang, Hsin-Yao, Speicher, David W., Zhang, Rugang

Abstract

Senescent cells exhibit dramatic changes in protein post-translational modifications. Here, we describe a method, stable isotope labeling with amino acids in cell culture (SILAC) coupled to liquid chromatography tandem mass spectrometry (LC-MS/MS), to identify changes in the ubiquitinome in cells that have undergone oncogene-induced senescence.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 33%
Student > Ph. D. Student 1 17%
Unknown 3 50%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 50%
Unknown 3 50%