Chapter title |
Gold Nanoparticles as Carriers for Synthetic Glycoconjugate Vaccines
|
---|---|
Chapter number | 10 |
Book title |
Carbohydrate-Based Vaccines
|
Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-2874-3_10 |
Pubmed ID | |
Book ISBNs |
978-1-4939-2873-6, 978-1-4939-2874-3
|
Authors |
Fabrizio Chiodo, Marco Marradi, Chiodo, Fabrizio, Marradi, Marco |
Abstract |
Recent advances in the preparation and characterization of metal core-based nanoparticles have opened the way to their exploration as carriers for carbohydrate-based vaccines. Here we describe the protocols for the preparation and characterization of water dispersible gold nanoparticles (1-3 nm gold diameter) as carriers for carbohydrate antigens. We mainly refer to the protocols we used for the preparation of gold glyconanoparticles as carrier for an S. pneumoniae carbohydrate-antigen. The high number of ligands at the gold nanoparticles surface and the easiness of their one-pot preparation make these biocompatible nanomaterials an attractive tool for glyco-scientists. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 27% |
Student > Master | 2 | 18% |
Professor | 1 | 9% |
Researcher | 1 | 9% |
Student > Postgraduate | 1 | 9% |
Other | 0 | 0% |
Unknown | 3 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 7 | 64% |
Agricultural and Biological Sciences | 1 | 9% |
Unknown | 3 | 27% |