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Carbohydrate-Based Vaccines

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Attention for Chapter 10: Gold Nanoparticles as Carriers for Synthetic Glycoconjugate Vaccines
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Chapter title
Gold Nanoparticles as Carriers for Synthetic Glycoconjugate Vaccines
Chapter number 10
Book title
Carbohydrate-Based Vaccines
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2874-3_10
Pubmed ID
Book ISBNs
978-1-4939-2873-6, 978-1-4939-2874-3
Authors

Fabrizio Chiodo, Marco Marradi, Chiodo, Fabrizio, Marradi, Marco

Abstract

Recent advances in the preparation and characterization of metal core-based nanoparticles have opened the way to their exploration as carriers for carbohydrate-based vaccines. Here we describe the protocols for the preparation and characterization of water dispersible gold nanoparticles (1-3 nm gold diameter) as carriers for carbohydrate antigens. We mainly refer to the protocols we used for the preparation of gold glyconanoparticles as carrier for an S. pneumoniae carbohydrate-antigen. The high number of ligands at the gold nanoparticles surface and the easiness of their one-pot preparation make these biocompatible nanomaterials an attractive tool for glyco-scientists.

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Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 27%
Student > Master 2 18%
Professor 1 9%
Researcher 1 9%
Student > Postgraduate 1 9%
Other 0 0%
Unknown 3 27%
Readers by discipline Count As %
Chemistry 7 64%
Agricultural and Biological Sciences 1 9%
Unknown 3 27%