| Chapter title |
Endocannabinoids and Metabolic Disorders.
|
|---|---|
| Chapter number | 13 |
| Book title |
Endocannabinoids
|
| Published in |
Handbook of experimental pharmacology, January 2015
|
| DOI | 10.1007/978-3-319-20825-1_13 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-920824-4, 978-3-31-920825-1
|
| Authors |
Gatta-Cherifi, Blandine, Cota, Daniela, Blandine Gatta-Cherifi, Daniela Cota |
| Editors |
Roger G. Pertwee |
| Abstract |
The endocannabinoid system (ECS) is known to exert regulatory control on essentially every aspect related to the search for, and the intake, metabolism and storage of calories, and consequently it represents a potential pharmacotherapeutic target for obesity, diabetes and eating disorders. While the clinical use of the first generation of cannabinoid type 1 (CB1) receptor blockers has been halted due to the psychiatric side effects that their use occasioned, recent research in animals and humans has provided new knowledge on the mechanisms of actions of the ECS in the regulation of eating behavior, energy balance, and metabolism. In this review, we discuss these recent advances and how they may allow targeting the ECS in a more specific and selective manner for the future development of therapies against obesity, metabolic syndrome, and eating disorders. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 8 | 12% |
| Student > Ph. D. Student | 8 | 12% |
| Student > Master | 8 | 12% |
| Student > Bachelor | 7 | 10% |
| Student > Doctoral Student | 7 | 10% |
| Other | 13 | 19% |
| Unknown | 17 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 9% |
| Biochemistry, Genetics and Molecular Biology | 5 | 7% |
| Neuroscience | 5 | 7% |
| Agricultural and Biological Sciences | 4 | 6% |
| Other | 12 | 18% |
| Unknown | 22 | 32% |