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Mendeley readers
| Chapter title |
Assembling Multi-subunit Complexes Using Mammalian Expression.
|
|---|---|
| Chapter number | 15 |
| Book title |
Advanced Technologies for Protein Complex Production and Characterization
|
| Published in |
Advances in experimental medicine and biology, May 2016
|
| DOI | 10.1007/978-3-319-27216-0_15 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-927214-6, 978-3-31-927216-0
|
| Authors |
Bahar Baser, Joop van den Heuvel |
| Editors |
M. Cristina Vega |
| Abstract |
In this chapter conventional and emerging new technologies for the production of complex biologics in mammalian expression systems are summarized. The essential features of the most relevant methods to generate stable production cell lines for the expression of recombinant multi-protein complexes are described. Especially the promising multiple targeted integration strategy by Flp or CRISPR/Cas9 mediated recombination and their future impact on multi-protein expression are highlighted. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 29% |
| Student > Doctoral Student | 5 | 16% |
| Student > Master | 4 | 13% |
| Professor | 1 | 3% |
| Lecturer > Senior Lecturer | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 9 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 32% |
| Agricultural and Biological Sciences | 4 | 13% |
| Chemical Engineering | 2 | 6% |
| Chemistry | 2 | 6% |
| Environmental Science | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 10 | 32% |