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Metabolic Control

Overview of attention for book
Cover of 'Metabolic Control'

Table of Contents

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    Book Overview
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    Chapter 1 Glucocorticoids and Metabolic Control.
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    Chapter 2 A Genome-Wide Perspective on Metabolism.
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    Chapter 3 cGMP and Brown Adipose Tissue.
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    Chapter 4 Signalling Networks Governing Metabolic Inflammation.
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    Chapter 5 Nuclear Receptor Coregulators in Metabolism and Disease.
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    Chapter 6 Adipokines and the Endocrine Role of Adipose Tissues.
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    Chapter 7 Current and Emerging Treatment Options in Diabetes Care.
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    Chapter 8 Immune Cells and Metabolism.
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    Chapter 9 Incretins
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    Chapter 10 Organ-Specific Cancer Metabolism and Its Potential for Therapy
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    Chapter 11 Brown Adipose Tissue: A Human Perspective.
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    Chapter 12 Metabolic Syndrome, Type 2 Diabetes, and Cancer: Epidemiology and Potential Mechanisms
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    Chapter 13 Adipose Tissue Stem Cells.
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    Chapter 14 Insulin Signaling in the Control of Glucose and Lipid Homeostasis.
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    Chapter 15 Antilipidemic Drug Therapy Today and in the Future.
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    Chapter 32 Role of the cAMP Pathway in Glucose and Lipid Metabolism.
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    Chapter 33 Neural Control of Energy Expenditure.
Attention for Chapter 9: Incretins
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89 Mendeley
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Chapter title
Incretins
Chapter number 9
Book title
Metabolic Control
Published in
Handbook of experimental pharmacology, January 2015
DOI 10.1007/164_2015_9
Pubmed ID
25903418
Book ISBNs
978-3-31-929804-7, 978-3-31-929806-1
Authors

Wu, Tongzhi, Rayner, Christopher K., Horowitz, Michael, Tongzhi Wu, Christopher K. Rayner, Michael Horowitz

Editors

Stephan Herzig

Abstract

Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the known incretin hormones in humans, released predominantly from the enteroendocrine K and L cells within the gut. Their secretion is regulated by a complex of integrated mechanisms involving direct contact for the activation of different chemo-sensors on the brush boarder of K and L cells and several indirect neuro-immuno-hormonal loops. The biological actions of GIP and GLP-1 are fundamental determinants of islet function and blood glucose homeostasis in health and type 2 diabetes. Moreover, there is increasing recognition that GIP and GLP-1 also exert pleiotropic extra-glycaemic actions, which may represent therapeutic targets for human diseases. In this review, we summarise current knowledge of the biology of incretin hormones in health and metabolic disorders and highlight the therapeutic potential of incretin hormones in metabolic regulation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iraq 1 1%
Chile 1 1%
Unknown 87 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 19%
Student > Bachelor 13 15%
Researcher 11 12%
Student > Ph. D. Student 9 10%
Professor > Associate Professor 4 4%
Other 13 15%
Unknown 22 25%
Readers by discipline Count As %
Medicine and Dentistry 28 31%
Biochemistry, Genetics and Molecular Biology 7 8%
Agricultural and Biological Sciences 7 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Nursing and Health Professions 4 4%
Other 13 15%
Unknown 26 29%

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