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Mendeley readers
| Chapter title |
TRPC Channels and Cell Proliferation
|
|---|---|
| Chapter number | 13 |
| Book title |
Transient Receptor Potential Canonical Channels and Brain Diseases
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-94-024-1088-4_13 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-241086-0, 978-9-40-241088-4
|
| Authors |
Cheng Zhan, Yu Shi, Zhan, Cheng, Shi, Yu |
| Abstract |
TRPCs have been demonstrated to be widely expressed in different cancers. In recent years, a number of studies closely investigated the roles of TRPCs in cancer cells. Most of the results show that both mRNA and protein levels of TRPCs significantly increase in cancer tissues compared with healthy controls. TRPCs regulate Ca(2+) homeostasis, contribute to cell cycle regulation and the expression/activation of Ca(2+)-related factors, and thus play critical roles in the proliferation of cancer cells. Therefore, TRPCs could act as potential drug targets for cancer diagnosis and therapy. |
Mendeley readers
The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 50% |
| Unknown | 2 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 1 | 25% |
| Medicine and Dentistry | 1 | 25% |
| Unknown | 2 | 50% |