Chapter title |
Neuroglia: Functional Paralysis and Reactivity in Alzheimer’s Disease and Other Neurodegenerative Pathologies
|
---|---|
Chapter number | 17 |
Book title |
Neurodegenerative Diseases
|
Published in |
Advances in neurobiology, July 2017
|
DOI | 10.1007/978-3-319-57193-5_17 |
Pubmed ID | |
Book ISBNs |
978-3-31-957191-1, 978-3-31-957193-5
|
Authors |
Alexei Verkhratsky, Robert Zorec, J. J. Rodriguez, Vladimir Parpura, Verkhratsky, Alexei, Zorec, Robert, Rodriguez, J. J., Parpura, Vladimir |
Abstract |
The most notable finding in neurodegenerative diseases is the progressive death of neurones cells. Yet, neuroglial changes can precede and facilitate neuronal loss. This is perhaps expected because astroglial cells maintain the brain homoeostasis, and are responsible for defence and regeneration, so that their malfunction manifested as degeneration or asthenia together with reactivity contribute to pathophysiology. Neuroglia may represent a novel target for therapeutic intervention, be that prevention, slowing progression of or possibly curing neurodegenerative diseases. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 35 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 20% |
Researcher | 4 | 11% |
Professor | 4 | 11% |
Student > Master | 3 | 9% |
Student > Bachelor | 2 | 6% |
Other | 4 | 11% |
Unknown | 11 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 8 | 23% |
Medicine and Dentistry | 4 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Business, Management and Accounting | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 5 | 14% |
Unknown | 14 | 40% |