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Neurodegenerative Diseases

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Cover of 'Neurodegenerative Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 Alzheimer’s Disease: Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons
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    Chapter 2 Clinical Aspects of Alzheimer’s Disease
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    Chapter 3 Parkinson’s Disease: Basic Pathomechanisms and a Clinical Overview
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    Chapter 4 Huntington’s Disease: Pathogenic Mechanisms and Therapeutic Targets
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    Chapter 5 The Complexity of Clinical Huntington’s Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers
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    Chapter 6 Motoneuron Disease: Basic Science
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    Chapter 7 Motoneuron Disease: Clinical
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    Chapter 8 Multiple Sclerosis: Basic and Clinical
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    Chapter 9 Schizophrenia: Basic and Clinical
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    Chapter 10 Stroke: Basic and Clinical
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    Chapter 11 Epileptic Encephalopathies as Neurodegenerative Disorders
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    Chapter 12 Neurodegeneration and Pathology in Epilepsy: Clinical and Basic Perspectives
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    Chapter 13 Prion Diseases
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    Chapter 14 Leukodystrophy: Basic and Clinical
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    Chapter 15 Traumatic Brain Injury as a Trigger of Neurodegeneration
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    Chapter 16 Cell Death Mechanisms of Neurodegeneration
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    Chapter 17 Neuroglia: Functional Paralysis and Reactivity in Alzheimer’s Disease and Other Neurodegenerative Pathologies
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    Chapter 18 Advances in Neuroimaging for Neurodegenerative Disease
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    Chapter 19 Gene Linkage and Systems Biology
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    Chapter 20 Biomarkers in Neurodegenerative Diseases
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    Chapter 21 Erratum
Attention for Chapter 17: Neuroglia: Functional Paralysis and Reactivity in Alzheimer’s Disease and Other Neurodegenerative Pathologies
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Citations

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Chapter title
Neuroglia: Functional Paralysis and Reactivity in Alzheimer’s Disease and Other Neurodegenerative Pathologies
Chapter number 17
Book title
Neurodegenerative Diseases
Published in
Advances in neurobiology, July 2017
DOI 10.1007/978-3-319-57193-5_17
Pubmed ID
Book ISBNs
978-3-31-957191-1, 978-3-31-957193-5
Authors

Alexei Verkhratsky, Robert Zorec, J. J. Rodriguez, Vladimir Parpura, Verkhratsky, Alexei, Zorec, Robert, Rodriguez, J. J., Parpura, Vladimir

Abstract

The most notable finding in neurodegenerative diseases is the progressive death of neurones cells. Yet, neuroglial changes can precede and facilitate neuronal loss. This is perhaps expected because astroglial cells maintain the brain homoeostasis, and are responsible for defence and regeneration, so that their malfunction manifested as degeneration or asthenia together with reactivity contribute to pathophysiology. Neuroglia may represent a novel target for therapeutic intervention, be that prevention, slowing progression of or possibly curing neurodegenerative diseases.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 20%
Researcher 4 11%
Professor 4 11%
Student > Master 3 9%
Student > Bachelor 2 6%
Other 4 11%
Unknown 11 31%
Readers by discipline Count As %
Neuroscience 8 23%
Medicine and Dentistry 4 11%
Biochemistry, Genetics and Molecular Biology 2 6%
Business, Management and Accounting 1 3%
Agricultural and Biological Sciences 1 3%
Other 5 14%
Unknown 14 40%