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Mendeley readers
| Chapter title |
Circulating Tumor Cells
|
|---|---|
| Chapter number | 18 |
| Book title |
Cancer Stem Cells
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7401-6_18 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7400-9, 978-1-4939-7401-6
|
| Authors |
Sebastián A. García, Jürgen Weitz, Sebastian Schölch |
| Abstract |
In most solid tumors, it is distant metastases rather than the primary tumor which limit the prognosis. Distant metastases are caused by circulating tumor cells (CTCs) which actively invade the blood stream, attach to the endothelium in the target organ, invade the surrounding parenchyma, and form new tumors. Among many other capabilities such as migration or immune escape, CTCs require tumor-forming capacities and can therefore be considered stem cell-like cells. This chapter describes the enrichment and isolation of live CTCs from clinical blood samples for molecular characterization and other downstream applications. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 56 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 18% |
| Researcher | 10 | 18% |
| Other | 6 | 11% |
| Student > Doctoral Student | 6 | 11% |
| Student > Bachelor | 5 | 9% |
| Other | 11 | 20% |
| Unknown | 8 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 27% |
| Biochemistry, Genetics and Molecular Biology | 14 | 25% |
| Agricultural and Biological Sciences | 6 | 11% |
| Engineering | 5 | 9% |
| Chemistry | 2 | 4% |
| Other | 4 | 7% |
| Unknown | 10 | 18% |