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Mendeley readers
Chapter title |
A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I Poisons
|
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Chapter number | 18 |
Book title |
DNA Topoisomerases
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Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7459-7_18 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7458-0, 978-1-4939-7459-7
|
Authors |
Thirunavukkarasu Annamalai, Bokun Cheng, Neelam Keswani, Yuk-Ching Tse-Dinh |
Abstract |
Bacterial Topoisomerase I is a potential target for the identification of novel topoisomerase poison inhibitors that could provide leads for a new class of antibacterial compounds. Here we describe in detail a fluorescence-based cleavage assay that is successfully used in HTS for the discovery of bacterial topoisomerase Ι poisons. |
Mendeley readers
The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 1 | 50% |
Unknown | 1 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 50% |
Unknown | 1 | 50% |