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Mendeley readers
Chapter title |
Protease Silencing to Explore the Molecular Mechanisms of Cancer and Aging
|
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Chapter number | 23 |
Book title |
Proteases and Cancer
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Published in |
Methods in molecular biology, January 2018
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DOI | 10.1007/978-1-4939-7595-2_23 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7594-5, 978-1-4939-7595-2
|
Authors |
Julia M. Fraile, Diana Campos-Iglesias, José M. P. Freije |
Abstract |
Proteases play key roles in the execution and regulation of most if not all biological functions, and alterations in their activity, expression, or location are associated with multiple pathological conditions, including cancer and aging. In this regard, the use of RNA interference-based approaches to specifically target the expression of individual proteases constitutes an invaluable tool to identify enzymes involved in central aspects of these processes and to explore their potential as targets of therapeutic interventions. Here we describe simple protocols to optimize and monitor the specific silencing of cancer- and aging-related proteases. |
Mendeley readers
The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 75% |
Professor | 1 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 75% |
Agricultural and Biological Sciences | 1 | 25% |